Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfected patients: significant associations with IL28B and SOCS3 gene variants.

Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfected patients: significant associations with IL28B and SOCS3 gene variants.

BACKGROUND AND AIMS:This was a safety and efficacy pharmacogenetic study of a previously performed randomized trial which compared the effectiveness of treatment of hepatitis C virus infection with pegylated interferon alpha (pegIFNα) 2a vs. 2b, both with ribavirin, for 48 weeks, in HCV-HIV coinfect...

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Main Authors: Francesc Vidal, Miguel López-Dupla, Montserrat Laguno, Sergi Veloso, Josep Mallolas, Javier Murillas, Carmen Cifuentes, Lluis Gallart, Teresa Auguet, Gloria Sampériz, Antoni Payeras, Pilar Hernandez, Mireia Arnedo, Josep Ma Gatell, Cristóbal Richart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3487790?pdf=render

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