N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis

N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis

Abstract Circular RNAs (circRNAs) are a recently discovered kind of regulatory RNAs that have emerged as critical biomarkers of various types of cancers. Metabolic reprogramming has gradually been identified as a distinct hallmark of cancer cells. The pentose phosphate pathway (PPP) plays an indispe...

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Bibliographic Details
Main Authors: Baoxiang Chen, Yuntian Hong, Rui Gui, Huabin Zheng, Shunhua Tian, Xiang Zhai, Xiaoyu Xie, Quanjiao Chen, Qun Qian, Xianghai Ren, Lifang Fan, Congqing Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05245-2

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