A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis
The goal of this study is to portray an initial experience with the efficacy, safety, and, acceptance of ARNI in ambulatory cardiology practices in India. The research is a retrospective review of single-centre data who began therapy with ARNI in HFrEF between 2019 and 2020. The analysis included da...
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Format: | Article |
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Elsevier
2021-03-01
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Series: | Indian Heart Journal |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S001948322100002X |
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author | Pankaj Jariwala Arshad Punjani Harikishan Boorugu Dilip Babu Madhawar |
author_facet | Pankaj Jariwala Arshad Punjani Harikishan Boorugu Dilip Babu Madhawar |
author_sort | Pankaj Jariwala |
collection | DOAJ |
description | The goal of this study is to portray an initial experience with the efficacy, safety, and, acceptance of ARNI in ambulatory cardiology practices in India. The research is a retrospective review of single-centre data who began therapy with ARNI in HFrEF between 2019 and 2020. The analysis included data for 454 symptomatic patients, aged 57 ± 20.8 years in NYHA class II-III. During follow-up, patients experienced significant improvement in HF symptoms determined by using Kansas City Cardiomyopathy Questionnaire (KCCQ) and a considerable reduction in NT-proBNP levels. ARNI is associated with substantial clinical benefit in an outpatient setting in HFrEF. |
first_indexed | 2024-12-22T20:22:13Z |
format | Article |
id | doaj.art-2546c22727d44c29ac0d8baf32bcd82f |
institution | Directory Open Access Journal |
issn | 0019-4832 |
language | English |
last_indexed | 2024-12-22T20:22:13Z |
publishDate | 2021-03-01 |
publisher | Elsevier |
record_format | Article |
series | Indian Heart Journal |
spelling | doaj.art-2546c22727d44c29ac0d8baf32bcd82f2022-12-21T18:13:49ZengElsevierIndian Heart Journal0019-48322021-03-01732211213A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basisPankaj Jariwala0Arshad Punjani1Harikishan Boorugu2Dilip Babu Madhawar3Consultant Cardiologist and Heart Failure Specialist, Department of Cardiology, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, India; Corresponding author. Department of Cardiology, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, India.Consultant Physician, Department of Internal Medicine, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, IndiaConsultant Physician, Department of Internal Medicine, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, IndiaConsultant Nephrologist and Transplant Physician, Department of Nephrology and Transplant Medicine, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, IndiaThe goal of this study is to portray an initial experience with the efficacy, safety, and, acceptance of ARNI in ambulatory cardiology practices in India. The research is a retrospective review of single-centre data who began therapy with ARNI in HFrEF between 2019 and 2020. The analysis included data for 454 symptomatic patients, aged 57 ± 20.8 years in NYHA class II-III. During follow-up, patients experienced significant improvement in HF symptoms determined by using Kansas City Cardiomyopathy Questionnaire (KCCQ) and a considerable reduction in NT-proBNP levels. ARNI is associated with substantial clinical benefit in an outpatient setting in HFrEF.http://www.sciencedirect.com/science/article/pii/S001948322100002XAngiotensin receptor-neprilysin inhibitorSacubitril/valsartanHeart failure with a reduced ejection fraction |
spellingShingle | Pankaj Jariwala Arshad Punjani Harikishan Boorugu Dilip Babu Madhawar A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis Indian Heart Journal Angiotensin receptor-neprilysin inhibitor Sacubitril/valsartan Heart failure with a reduced ejection fraction |
title | A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis |
title_full | A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis |
title_fullStr | A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis |
title_full_unstemmed | A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis |
title_short | A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis |
title_sort | clinical experience of indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor neprilysin inhibitor arni on an outpatient basis |
topic | Angiotensin receptor-neprilysin inhibitor Sacubitril/valsartan Heart failure with a reduced ejection fraction |
url | http://www.sciencedirect.com/science/article/pii/S001948322100002X |
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