A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis

The goal of this study is to portray an initial experience with the efficacy, safety, and, acceptance of ARNI in ambulatory cardiology practices in India. The research is a retrospective review of single-centre data who began therapy with ARNI in HFrEF between 2019 and 2020. The analysis included da...

Full description

Bibliographic Details
Main Authors: Pankaj Jariwala, Arshad Punjani, Harikishan Boorugu, Dilip Babu Madhawar
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Indian Heart Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S001948322100002X
_version_ 1819173383738228736
author Pankaj Jariwala
Arshad Punjani
Harikishan Boorugu
Dilip Babu Madhawar
author_facet Pankaj Jariwala
Arshad Punjani
Harikishan Boorugu
Dilip Babu Madhawar
author_sort Pankaj Jariwala
collection DOAJ
description The goal of this study is to portray an initial experience with the efficacy, safety, and, acceptance of ARNI in ambulatory cardiology practices in India. The research is a retrospective review of single-centre data who began therapy with ARNI in HFrEF between 2019 and 2020. The analysis included data for 454 symptomatic patients, aged 57 ± 20.8 years in NYHA class II-III. During follow-up, patients experienced significant improvement in HF symptoms determined by using Kansas City Cardiomyopathy Questionnaire (KCCQ) and a considerable reduction in NT-proBNP levels. ARNI is associated with substantial clinical benefit in an outpatient setting in HFrEF.
first_indexed 2024-12-22T20:22:13Z
format Article
id doaj.art-2546c22727d44c29ac0d8baf32bcd82f
institution Directory Open Access Journal
issn 0019-4832
language English
last_indexed 2024-12-22T20:22:13Z
publishDate 2021-03-01
publisher Elsevier
record_format Article
series Indian Heart Journal
spelling doaj.art-2546c22727d44c29ac0d8baf32bcd82f2022-12-21T18:13:49ZengElsevierIndian Heart Journal0019-48322021-03-01732211213A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basisPankaj Jariwala0Arshad Punjani1Harikishan Boorugu2Dilip Babu Madhawar3Consultant Cardiologist and Heart Failure Specialist, Department of Cardiology, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, India; Corresponding author. Department of Cardiology, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, India.Consultant Physician, Department of Internal Medicine, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, IndiaConsultant Physician, Department of Internal Medicine, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, IndiaConsultant Nephrologist and Transplant Physician, Department of Nephrology and Transplant Medicine, Yashoda Hospitals, Somajiguda, Raj Bhavan Road, Hyderabad, Telangana, 500082, IndiaThe goal of this study is to portray an initial experience with the efficacy, safety, and, acceptance of ARNI in ambulatory cardiology practices in India. The research is a retrospective review of single-centre data who began therapy with ARNI in HFrEF between 2019 and 2020. The analysis included data for 454 symptomatic patients, aged 57 ± 20.8 years in NYHA class II-III. During follow-up, patients experienced significant improvement in HF symptoms determined by using Kansas City Cardiomyopathy Questionnaire (KCCQ) and a considerable reduction in NT-proBNP levels. ARNI is associated with substantial clinical benefit in an outpatient setting in HFrEF.http://www.sciencedirect.com/science/article/pii/S001948322100002XAngiotensin receptor-neprilysin inhibitorSacubitril/valsartanHeart failure with a reduced ejection fraction
spellingShingle Pankaj Jariwala
Arshad Punjani
Harikishan Boorugu
Dilip Babu Madhawar
A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis
Indian Heart Journal
Angiotensin receptor-neprilysin inhibitor
Sacubitril/valsartan
Heart failure with a reduced ejection fraction
title A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis
title_full A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis
title_fullStr A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis
title_full_unstemmed A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis
title_short A clinical experience of Indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor-neprilysin inhibitor [ARNI] on an outpatient basis
title_sort clinical experience of indian patients with heart failure with reduced left ventricular ejection fraction using an angiotensin receptor neprilysin inhibitor arni on an outpatient basis
topic Angiotensin receptor-neprilysin inhibitor
Sacubitril/valsartan
Heart failure with a reduced ejection fraction
url http://www.sciencedirect.com/science/article/pii/S001948322100002X
work_keys_str_mv AT pankajjariwala aclinicalexperienceofindianpatientswithheartfailurewithreducedleftventricularejectionfractionusinganangiotensinreceptorneprilysininhibitorarnionanoutpatientbasis
AT arshadpunjani aclinicalexperienceofindianpatientswithheartfailurewithreducedleftventricularejectionfractionusinganangiotensinreceptorneprilysininhibitorarnionanoutpatientbasis
AT harikishanboorugu aclinicalexperienceofindianpatientswithheartfailurewithreducedleftventricularejectionfractionusinganangiotensinreceptorneprilysininhibitorarnionanoutpatientbasis
AT dilipbabumadhawar aclinicalexperienceofindianpatientswithheartfailurewithreducedleftventricularejectionfractionusinganangiotensinreceptorneprilysininhibitorarnionanoutpatientbasis
AT pankajjariwala clinicalexperienceofindianpatientswithheartfailurewithreducedleftventricularejectionfractionusinganangiotensinreceptorneprilysininhibitorarnionanoutpatientbasis
AT arshadpunjani clinicalexperienceofindianpatientswithheartfailurewithreducedleftventricularejectionfractionusinganangiotensinreceptorneprilysininhibitorarnionanoutpatientbasis
AT harikishanboorugu clinicalexperienceofindianpatientswithheartfailurewithreducedleftventricularejectionfractionusinganangiotensinreceptorneprilysininhibitorarnionanoutpatientbasis
AT dilipbabumadhawar clinicalexperienceofindianpatientswithheartfailurewithreducedleftventricularejectionfractionusinganangiotensinreceptorneprilysininhibitorarnionanoutpatientbasis