Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency Department

Aim:Renal colic is a urological emergency usually caused by urolithiasis and manifested by severe pain. Emergency treatment’s main purpose is to effectively relieve pain and urinary obstruction without impaired renal function. We measured the efficacy and safety of intravenous ibuprofen on renal col...

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Main Authors: Murat Özdemir, Gülşen Çığşar, Murat Bağcıoğlu, Handan Çiftçi, Elnare Günal
Format: Article
Language:English
Published: Galenos Yayinevi 2023-03-01
Series:Eurasian Journal of Emergency Medicine
Subjects:
Online Access: http://eajem.com/archives/archive-detail/article-preview/comparison-of-the-analgesic-effects-of-ntravenous-/58819
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author Murat Özdemir
Gülşen Çığşar
Murat Bağcıoğlu
Handan Çiftçi
Elnare Günal
author_facet Murat Özdemir
Gülşen Çığşar
Murat Bağcıoğlu
Handan Çiftçi
Elnare Günal
author_sort Murat Özdemir
collection DOAJ
description Aim:Renal colic is a urological emergency usually caused by urolithiasis and manifested by severe pain. Emergency treatment’s main purpose is to effectively relieve pain and urinary obstruction without impaired renal function. We measured the efficacy and safety of intravenous ibuprofen on renal colic pain.Materials and Methods:Two-hundred thirty-five patients who were admitted to the emergency department between 01.01.2016-30.06.2017 and were suspected of renal colic that scored at least 2 points on the visual analog scale (VAS) or FLACC scale were included in the study after obtaining detailed consent. One hundred-fifty four patients whose diagnoses were confirmed radiologically, included in the study as Group A (dexketoprofen) (n=35), Group B (ibuprofen 400 mg) (n=37), Group C (ibuprofen 800 mg) (n=44), and Group D (fentanyl) (n=38). VAS and FLACC scales were re-evaluated on the 20th, 40th, and 60th minutes after drug administration.Results:64.9% of the patients were male and 35.1% were female, and the mean age was 42.31 (±15.46). It was observed that all 4 of the medications given to patients who applied to the emergency department with flank pain provided effective analgesia, but the drugs could not establish a statistically significant advantage over each other.Conclusion:Intravenous administration of ibuprofen is considered as an effective and safe alternative in the treatment of renal colic pain in the emergency department.
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spelling doaj.art-2547164b68e6436a8986cb05eaa648402023-03-06T12:19:23ZengGalenos YayineviEurasian Journal of Emergency Medicine2149-58072149-60482023-03-01221182310.4274/eajem.galenos.2022.2063313049054Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency DepartmentMurat Özdemir0Gülşen Çığşar1Murat Bağcıoğlu2Handan Çiftçi3Elnare Günal4 Uşak Training and Research Hospital, Clinic of Emergency Medicine, Uşak, Turkey University of Health Sciences Turkey, Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Clinic of Emergency Medicine, Ankara, Turkey Kafkas University Health, Research and Application Center, Department of Urology, Kars, Turkey Kafkas University Health, Research and Application Center, Department of Emergency Medicine, Kars, Turkey Rize Training and Research Hospital, Clinic of Emergency Medicine, Rize, Turkey Aim:Renal colic is a urological emergency usually caused by urolithiasis and manifested by severe pain. Emergency treatment’s main purpose is to effectively relieve pain and urinary obstruction without impaired renal function. We measured the efficacy and safety of intravenous ibuprofen on renal colic pain.Materials and Methods:Two-hundred thirty-five patients who were admitted to the emergency department between 01.01.2016-30.06.2017 and were suspected of renal colic that scored at least 2 points on the visual analog scale (VAS) or FLACC scale were included in the study after obtaining detailed consent. One hundred-fifty four patients whose diagnoses were confirmed radiologically, included in the study as Group A (dexketoprofen) (n=35), Group B (ibuprofen 400 mg) (n=37), Group C (ibuprofen 800 mg) (n=44), and Group D (fentanyl) (n=38). VAS and FLACC scales were re-evaluated on the 20th, 40th, and 60th minutes after drug administration.Results:64.9% of the patients were male and 35.1% were female, and the mean age was 42.31 (±15.46). It was observed that all 4 of the medications given to patients who applied to the emergency department with flank pain provided effective analgesia, but the drugs could not establish a statistically significant advantage over each other.Conclusion:Intravenous administration of ibuprofen is considered as an effective and safe alternative in the treatment of renal colic pain in the emergency department. http://eajem.com/archives/archive-detail/article-preview/comparison-of-the-analgesic-effects-of-ntravenous-/58819 analgesiadexketoprofenfentanylibuprofenrenal colic
spellingShingle Murat Özdemir
Gülşen Çığşar
Murat Bağcıoğlu
Handan Çiftçi
Elnare Günal
Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency Department
Eurasian Journal of Emergency Medicine
analgesia
dexketoprofen
fentanyl
ibuprofen
renal colic
title Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency Department
title_full Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency Department
title_fullStr Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency Department
title_full_unstemmed Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency Department
title_short Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency Department
title_sort comparison of the analgesic effects of intravenous dexketoprofen ibuprofen and fentanyl in patients suffering from renal colic pain in the emergency department
topic analgesia
dexketoprofen
fentanyl
ibuprofen
renal colic
url http://eajem.com/archives/archive-detail/article-preview/comparison-of-the-analgesic-effects-of-ntravenous-/58819
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