Burkitt's lymphoma: The prevalence of HIV/AIDS and the outcome of treatment
The prevalence of HIV in Burkitt’s lymphoma (BL) patients and the outcome of treatment in Cameroon were unknown. Records of all patients diagnosed with BL at three Cameroon Baptist Convention hospitals were reviewed to ascertain the recorded HIV status and outcome of treatment. Of 979 patients dia...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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South African Medical Association
2018-02-01
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| Series: | South African Medical Journal |
| Online Access: | http://www.samj.org.za/index.php/samj/article/download/12190/8371 |
| _version_ | 1797334915348430848 |
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| author | F Kouya P Hesseling G Mbah E Katayi P Wharin |
| author_facet | F Kouya P Hesseling G Mbah E Katayi P Wharin |
| author_sort | F Kouya |
| collection | DOAJ |
| description | The prevalence of HIV in Burkitt’s lymphoma (BL) patients and the outcome of treatment in Cameroon were unknown. Records of all patients diagnosed with BL at three Cameroon Baptist Convention hospitals were reviewed to ascertain the recorded HIV status and outcome of treatment. Of 979 patients diagnosed with BL, 717 were tested for HIV and 11 (1.5%) were HIV-positive. Three of eight patients treated with both cyclophosphamide (CPM)-based chemotherapy and antiretrovirals were alive at 62, 96 and 111 months, respectively. The HIV rate was comparable to that of 1% for the general population of children aged <15 years. Low-cost high-frequency CPM was the only available treatment option for BL and was associated with 37.5% long-term survival in a resource-limited setting. |
| first_indexed | 2024-03-08T08:29:08Z |
| format | Article |
| id | doaj.art-254717d45bd64f0ba655215024b58cdc |
| institution | Directory Open Access Journal |
| issn | 0256-9574 2078-5135 |
| language | English |
| last_indexed | 2024-03-08T08:29:08Z |
| publishDate | 2018-02-01 |
| publisher | South African Medical Association |
| record_format | Article |
| series | South African Medical Journal |
| spelling | doaj.art-254717d45bd64f0ba655215024b58cdc2024-02-02T03:40:18ZengSouth African Medical AssociationSouth African Medical Journal0256-95742078-51352018-02-011082848510.7196/SAMJ.2018.v108i2.12441Burkitt's lymphoma: The prevalence of HIV/AIDS and the outcome of treatmentF KouyaP HesselingG MbahE KatayiP WharinThe prevalence of HIV in Burkitt’s lymphoma (BL) patients and the outcome of treatment in Cameroon were unknown. Records of all patients diagnosed with BL at three Cameroon Baptist Convention hospitals were reviewed to ascertain the recorded HIV status and outcome of treatment. Of 979 patients diagnosed with BL, 717 were tested for HIV and 11 (1.5%) were HIV-positive. Three of eight patients treated with both cyclophosphamide (CPM)-based chemotherapy and antiretrovirals were alive at 62, 96 and 111 months, respectively. The HIV rate was comparable to that of 1% for the general population of children aged <15 years. Low-cost high-frequency CPM was the only available treatment option for BL and was associated with 37.5% long-term survival in a resource-limited setting.http://www.samj.org.za/index.php/samj/article/download/12190/8371 |
| spellingShingle | F Kouya P Hesseling G Mbah E Katayi P Wharin Burkitt's lymphoma: The prevalence of HIV/AIDS and the outcome of treatment South African Medical Journal |
| title | Burkitt's lymphoma: The prevalence of HIV/AIDS and the outcome of treatment |
| title_full | Burkitt's lymphoma: The prevalence of HIV/AIDS and the outcome of treatment |
| title_fullStr | Burkitt's lymphoma: The prevalence of HIV/AIDS and the outcome of treatment |
| title_full_unstemmed | Burkitt's lymphoma: The prevalence of HIV/AIDS and the outcome of treatment |
| title_short | Burkitt's lymphoma: The prevalence of HIV/AIDS and the outcome of treatment |
| title_sort | burkitt s lymphoma the prevalence of hiv aids and the outcome of treatment |
| url | http://www.samj.org.za/index.php/samj/article/download/12190/8371 |
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