Complement activation contributes to perioperative neurocognitive disorders in mice

Complement activation contributes to perioperative neurocognitive disorders in mice

Abstract Background The complement system plays an important role in many neurological disorders. Complement modulation, including C3/C3a receptor signaling, shows promising therapeutic effects on cognition and neurodegeneration. Yet, the implications for this pathway in perioperative neurocognitive...

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Bibliographic Details
Main Authors: Chao Xiong, Jinhu Liu, Dandan Lin, Juxia Zhang, Niccolò Terrando, Anshi Wu
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Neuroinflammation
Subjects:
Choroid plexus
Complement
Hippocampus
Neuroinflammation
Perioperative neurocognitive disorders
Online Access:http://link.springer.com/article/10.1186/s12974-018-1292-4

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