Effect of novel synthesised policosanyl phenolates on lipid oxidation
Lipophilic derivatisation of phenolic acids could greatly improve their antioxidant activities and solubility in hydrophobic environments, broadening their applications in food, pharmaceutical, and cosmetic industries. In this study, we conducted enzymatic lipophilisation of eight phenolates with po...
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2016-10-01
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| Series: | Czech Journal of Food Sciences |
| Subjects: | |
| Online Access: | https://cjfs.agriculturejournals.cz/artkey/cjf-201605-0005_effect-of-novel-synthesised-policosanyl-phenolates-on-lipid-oxidation.php |
| _version_ | 1797899657844621312 |
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| author | Zhiqiang WANG Seung Hwan HWANG Soon Sung LIM |
| author_facet | Zhiqiang WANG Seung Hwan HWANG Soon Sung LIM |
| author_sort | Zhiqiang WANG |
| collection | DOAJ |
| description | Lipophilic derivatisation of phenolic acids could greatly improve their antioxidant activities and solubility in hydrophobic environments, broadening their applications in food, pharmaceutical, and cosmetic industries. In this study, we conducted enzymatic lipophilisation of eight phenolates with policosanols. Vinyl phenolates were used as intermediates to improve the efficiency of enzymatic lipophilisation; and the yields of policosanyl phenolates were in the range of 1.32-20.58%. The antioxidant activities of the resulting phenolipids were compared using 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assay and linoleic acid peroxidation ferric thiocyanate assay. The synthesised policosanyl phenolates showed lower ABTS radical scavenging capacities (IC50s > 15 mM); whereas they showed high lipid peroxidation inhibitory activities (IC50s of peroxidation value < 0.25 mM). The lipid oxidation inhibitory activities of policosanol phenolates were further evaluated using the total oxidation value in a linoleic acid model system and the thiobarbituric acid reactive substances value in a cooked pork model system. Finally, policosanyl 4-hydroxybenzoate, policosanyl syringate, and policosanyl 4-hydroxyphenylacetate showed the highest inhibition effects on lipid oxidation and a potential for use as lipid antioxidants. |
| first_indexed | 2024-04-10T08:32:26Z |
| format | Article |
| id | doaj.art-254a93d545b7412384b6a7ce0454f0e2 |
| institution | Directory Open Access Journal |
| issn | 1212-1800 1805-9317 |
| language | English |
| last_indexed | 2024-04-10T08:32:26Z |
| publishDate | 2016-10-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Czech Journal of Food Sciences |
| spelling | doaj.art-254a93d545b7412384b6a7ce0454f0e22023-02-23T03:28:20ZengCzech Academy of Agricultural SciencesCzech Journal of Food Sciences1212-18001805-93172016-10-0134541442110.17221/530/2015-CJFScjf-201605-0005Effect of novel synthesised policosanyl phenolates on lipid oxidationZhiqiang WANG0Seung Hwan HWANG1Soon Sung LIM2Department of Food Science and NutritionDepartment of Food Science and NutritionDepartment of Food Science and NutritionLipophilic derivatisation of phenolic acids could greatly improve their antioxidant activities and solubility in hydrophobic environments, broadening their applications in food, pharmaceutical, and cosmetic industries. In this study, we conducted enzymatic lipophilisation of eight phenolates with policosanols. Vinyl phenolates were used as intermediates to improve the efficiency of enzymatic lipophilisation; and the yields of policosanyl phenolates were in the range of 1.32-20.58%. The antioxidant activities of the resulting phenolipids were compared using 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assay and linoleic acid peroxidation ferric thiocyanate assay. The synthesised policosanyl phenolates showed lower ABTS radical scavenging capacities (IC50s > 15 mM); whereas they showed high lipid peroxidation inhibitory activities (IC50s of peroxidation value < 0.25 mM). The lipid oxidation inhibitory activities of policosanol phenolates were further evaluated using the total oxidation value in a linoleic acid model system and the thiobarbituric acid reactive substances value in a cooked pork model system. Finally, policosanyl 4-hydroxybenzoate, policosanyl syringate, and policosanyl 4-hydroxyphenylacetate showed the highest inhibition effects on lipid oxidation and a potential for use as lipid antioxidants.https://cjfs.agriculturejournals.cz/artkey/cjf-201605-0005_effect-of-novel-synthesised-policosanyl-phenolates-on-lipid-oxidation.phpnovozyme 435lipophilisationpolicosanolsphenolic acidsantioxidan |
| spellingShingle | Zhiqiang WANG Seung Hwan HWANG Soon Sung LIM Effect of novel synthesised policosanyl phenolates on lipid oxidation Czech Journal of Food Sciences novozyme 435 lipophilisation policosanols phenolic acids antioxidan |
| title | Effect of novel synthesised policosanyl phenolates on lipid oxidation |
| title_full | Effect of novel synthesised policosanyl phenolates on lipid oxidation |
| title_fullStr | Effect of novel synthesised policosanyl phenolates on lipid oxidation |
| title_full_unstemmed | Effect of novel synthesised policosanyl phenolates on lipid oxidation |
| title_short | Effect of novel synthesised policosanyl phenolates on lipid oxidation |
| title_sort | effect of novel synthesised policosanyl phenolates on lipid oxidation |
| topic | novozyme 435 lipophilisation policosanols phenolic acids antioxidan |
| url | https://cjfs.agriculturejournals.cz/artkey/cjf-201605-0005_effect-of-novel-synthesised-policosanyl-phenolates-on-lipid-oxidation.php |
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