Study of the antitumor mechanisms of apiole derivatives (AP-02) from Petroselinum crispum through induction of G0/G1 phase cell cycle arrest in human COLO 205 cancer cells

Study of the antitumor mechanisms of apiole derivatives (AP-02) from Petroselinum crispum through induction of G0/G1 phase cell cycle arrest in human COLO 205 cancer cells

Abstract Background Apiole was isolated from the leaves of various plants and vegetables and has been demonstrated to inhibit human colon cancer cell (COLO 205 cells) growth through induction of G0/G1 cell cycle arrest and apoptotic cell death. This study further explored the antitumor effects of ap...

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Bibliographic Details
Main Authors: Kuan-Hsun Wu, Wen-Jui Lee, Tzu-Chun Cheng, Hui-Wen Chang, Li-Ching Chen, Chia-Chang Chen, Hsiu-Man Lien, Teng-Nan Lin, Yuan-Soon Ho
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Apiole
COLO 205
Antitumor
Petroselinum crispum
G0/G1 arrest
Online Access:http://link.springer.com/article/10.1186/s12906-019-2590-9

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