Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease
(1) Purpose: to compare right ventricular (RV) functional parameters in children with surgically repaired congenital heart disease (CHD) using single/double breath hold (BH) and free-breathing (FB) real-time compressed sensing (CS) cine cardiac magnetic resonance (cMRI) with standard retrospective s...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/14/2403 |
| _version_ | 1797589641804644352 |
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| author | Christoph Treutlein Martin Georg Zeilinger Sven Dittrich Jan-Peter Roth Matthias Wetzl Rafael Heiss Wolfgang Wuest Matthias Stefan May Michael Uder Oliver Rompel |
| author_facet | Christoph Treutlein Martin Georg Zeilinger Sven Dittrich Jan-Peter Roth Matthias Wetzl Rafael Heiss Wolfgang Wuest Matthias Stefan May Michael Uder Oliver Rompel |
| author_sort | Christoph Treutlein |
| collection | DOAJ |
| description | (1) Purpose: to compare right ventricular (RV) functional parameters in children with surgically repaired congenital heart disease (CHD) using single/double breath hold (BH) and free-breathing (FB) real-time compressed sensing (CS) cine cardiac magnetic resonance (cMRI) with standard retrospective segmented multi breath hold (RMB) cine cMRI. (2) Methods: Twenty patients with CHD underwent BH and FB, as well as RMB cine cMRI, at 3T to obtain a stack of continuous axial images of the RV. Two radiologists independently performed qualitative analysis of the image quality (rated on a 5-point scale; 1 = non-diagnostic to 5 = excellent) and quantitative analysis of the RV volume measurements. (3) Results: The best image quality was provided by RMB (4.5; range 2–5) compared to BH (3.9; range 3–5; <i>p</i> = 0.04) and FB (3.6; range 3–5; <i>p</i> < 0.01). The RV functional parameters were comparable among BH, FB, and RMB with a difference of less than 5%. The scan times for BH (44 ± 38 s, <i>p</i> < 0.01) and FB (24 ± 7 s, <i>p</i> < 0.01) were significantly reduced compared to for RMB (261 ± 68 s). (4) Conclusions: CS-FB and CS-BH real-time cine cMRI in children with CHD provides diagnostic image quality with excellent accuracy for measuring RV function with a significantly reduced scan time compared to RMB. |
| first_indexed | 2024-03-11T01:09:28Z |
| format | Article |
| id | doaj.art-254c8c8c5bb245a9b08b303b9ea656d1 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T01:09:28Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-254c8c8c5bb245a9b08b303b9ea656d12023-11-18T18:58:19ZengMDPI AGDiagnostics2075-44182023-07-011314240310.3390/diagnostics13142403Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart DiseaseChristoph Treutlein0Martin Georg Zeilinger1Sven Dittrich2Jan-Peter Roth3Matthias Wetzl4Rafael Heiss5Wolfgang Wuest6Matthias Stefan May7Michael Uder8Oliver Rompel9Institute of Radiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyInstitute of Radiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyDepartment of Pediatric Cardiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyInstitute of Radiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyInstitute of Radiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyInstitute of Radiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyMartha-Maria Hospital, 90491 Nuremberg, GermanyInstitute of Radiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyInstitute of Radiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyInstitute of Radiology, University Hospital of Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany(1) Purpose: to compare right ventricular (RV) functional parameters in children with surgically repaired congenital heart disease (CHD) using single/double breath hold (BH) and free-breathing (FB) real-time compressed sensing (CS) cine cardiac magnetic resonance (cMRI) with standard retrospective segmented multi breath hold (RMB) cine cMRI. (2) Methods: Twenty patients with CHD underwent BH and FB, as well as RMB cine cMRI, at 3T to obtain a stack of continuous axial images of the RV. Two radiologists independently performed qualitative analysis of the image quality (rated on a 5-point scale; 1 = non-diagnostic to 5 = excellent) and quantitative analysis of the RV volume measurements. (3) Results: The best image quality was provided by RMB (4.5; range 2–5) compared to BH (3.9; range 3–5; <i>p</i> = 0.04) and FB (3.6; range 3–5; <i>p</i> < 0.01). The RV functional parameters were comparable among BH, FB, and RMB with a difference of less than 5%. The scan times for BH (44 ± 38 s, <i>p</i> < 0.01) and FB (24 ± 7 s, <i>p</i> < 0.01) were significantly reduced compared to for RMB (261 ± 68 s). (4) Conclusions: CS-FB and CS-BH real-time cine cMRI in children with CHD provides diagnostic image quality with excellent accuracy for measuring RV function with a significantly reduced scan time compared to RMB.https://www.mdpi.com/2075-4418/13/14/2403cardiac magnetic resonance imagingchildrencompressed sensing |
| spellingShingle | Christoph Treutlein Martin Georg Zeilinger Sven Dittrich Jan-Peter Roth Matthias Wetzl Rafael Heiss Wolfgang Wuest Matthias Stefan May Michael Uder Oliver Rompel Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease Diagnostics cardiac magnetic resonance imaging children compressed sensing |
| title | Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease |
| title_full | Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease |
| title_fullStr | Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease |
| title_full_unstemmed | Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease |
| title_short | Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease |
| title_sort | free breathing and single breath hold compressed sensing real time mri of right ventricular function in children with congenital heart disease |
| topic | cardiac magnetic resonance imaging children compressed sensing |
| url | https://www.mdpi.com/2075-4418/13/14/2403 |
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