Pathogenetic substantiation of combination therapy for rosacea

Rosacea is a chronic inflammatory dermatosis predominantly damage to the skin of the face, which has a significant negative impact on the quality patients’ lives. The main goal of treatment is to achieve the most complete remission. However, due to the fact that the pathogenesis of the disease is no...

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Main Authors: Alexey A. Kubanov, Xenia I. Plakhova, Irina N. Kondrakhina, Sofia V. Volkova
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2023-12-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
Online Access:https://vestnikdv.ru/jour/article/viewFile/8538/pdf
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author Alexey A. Kubanov
Xenia I. Plakhova
Irina N. Kondrakhina
Sofia V. Volkova
author_facet Alexey A. Kubanov
Xenia I. Plakhova
Irina N. Kondrakhina
Sofia V. Volkova
author_sort Alexey A. Kubanov
collection DOAJ
description Rosacea is a chronic inflammatory dermatosis predominantly damage to the skin of the face, which has a significant negative impact on the quality patients’ lives. The main goal of treatment is to achieve the most complete remission. However, due to the fact that the pathogenesis of the disease is not fully understood, the search for new methods of treatment is especially relevant. Combined use pulsed dye laser and ivermectin drug is presented as alternative pathogenetically substantiated method of therapy. The purpose of the study is to characterize immune disorders and the role of cytokines in the pathogenesis of rosacea, as well as the possibilities of combination therapy based on literature data. An analysis of literature sources from the MedLine, Pubmed, eLibrary databases for the period from 2002 to 2022 was carried out, using the keywords “ivermectin”, “pulsed dye laser”, “rosacea”, “cytokines”, “ivermectin” , “Pulsed Dye Laser”, “rosacea”, “cytokines”.
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spelling doaj.art-254d4695d95e4b38b231d5a35a59b82e2023-12-20T21:29:14ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942023-12-01995132110.25208/vdv85381232Pathogenetic substantiation of combination therapy for rosaceaAlexey A. Kubanov0https://orcid.org/0000-0002-7625-0503Xenia I. Plakhova1https://orcid.org/0000-0003-4169-4128Irina N. Kondrakhina2https://orcid.org/0000-0003-3662-9954Sofia V. Volkova3https://orcid.org/0009-0005-3155-0923State Research Center of Dermatovenereology and CosmetologyState Research Center of Dermatovenereology and CosmetologyState Research Center of Dermatovenereology and CosmetologyState Research Center of Dermatovenereology and CosmetologyRosacea is a chronic inflammatory dermatosis predominantly damage to the skin of the face, which has a significant negative impact on the quality patients’ lives. The main goal of treatment is to achieve the most complete remission. However, due to the fact that the pathogenesis of the disease is not fully understood, the search for new methods of treatment is especially relevant. Combined use pulsed dye laser and ivermectin drug is presented as alternative pathogenetically substantiated method of therapy. The purpose of the study is to characterize immune disorders and the role of cytokines in the pathogenesis of rosacea, as well as the possibilities of combination therapy based on literature data. An analysis of literature sources from the MedLine, Pubmed, eLibrary databases for the period from 2002 to 2022 was carried out, using the keywords “ivermectin”, “pulsed dye laser”, “rosacea”, “cytokines”, “ivermectin” , “Pulsed Dye Laser”, “rosacea”, “cytokines”.https://vestnikdv.ru/jour/article/viewFile/8538/pdfrosaceaivermectinpulsed dye lasercytokinescombination therapy
spellingShingle Alexey A. Kubanov
Xenia I. Plakhova
Irina N. Kondrakhina
Sofia V. Volkova
Pathogenetic substantiation of combination therapy for rosacea
Vestnik Dermatologii i Venerologii
rosacea
ivermectin
pulsed dye laser
cytokines
combination therapy
title Pathogenetic substantiation of combination therapy for rosacea
title_full Pathogenetic substantiation of combination therapy for rosacea
title_fullStr Pathogenetic substantiation of combination therapy for rosacea
title_full_unstemmed Pathogenetic substantiation of combination therapy for rosacea
title_short Pathogenetic substantiation of combination therapy for rosacea
title_sort pathogenetic substantiation of combination therapy for rosacea
topic rosacea
ivermectin
pulsed dye laser
cytokines
combination therapy
url https://vestnikdv.ru/jour/article/viewFile/8538/pdf
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AT irinankondrakhina pathogeneticsubstantiationofcombinationtherapyforrosacea
AT sofiavvolkova pathogeneticsubstantiationofcombinationtherapyforrosacea