POWERbreathe<sup>®</sup> Inspiratory Muscle Training in Amyotrophic Lateral Sclerosis
Inspiratory muscle training may benefit respiratory function, cardiocirculatory parameters, quality of life and functionality in neuromuscular diseases. This pilot study aimed to demonstrate the POWERbreathe<sup>®</sup> inspiratory muscle training effects on maximum inspiratory pressure...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/22/6655 |
| _version_ | 1797464948538867712 |
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| author | Davinia Vicente-Campos Sandra Sanchez-Jorge J. L. Chicharro Ricardo Becerro-de Bengoa-Vallejo David Rodriguez-Sanz Arianne R. García Marie Rivoire Astrid Benet Sofía Boubekeur César Calvo-Lobo |
| author_facet | Davinia Vicente-Campos Sandra Sanchez-Jorge J. L. Chicharro Ricardo Becerro-de Bengoa-Vallejo David Rodriguez-Sanz Arianne R. García Marie Rivoire Astrid Benet Sofía Boubekeur César Calvo-Lobo |
| author_sort | Davinia Vicente-Campos |
| collection | DOAJ |
| description | Inspiratory muscle training may benefit respiratory function, cardiocirculatory parameters, quality of life and functionality in neuromuscular diseases. This pilot study aimed to demonstrate the POWERbreathe<sup>®</sup> inspiratory muscle training effects on maximum inspiratory pressure (PI<sub>max</sub>), heart rate (HR) and HR variability, as well as the quality of life impairment and functionality in patients with Amyotrophic Lateral Sclerosis (ALS). A pilot single-blinded, non-randomized controlled clinical trial was carried out. A total of 20T ALS patients were enrolled and divided into experimental (<i>n</i> = 10) and control (<i>n</i> = 10) groups. The experimental group received POWERbreathe<sup>®</sup> inspiratory muscle training in conjunction with usual care, and the control group received only usual care for 8 weeks. PI<sub>max</sub> (measured by POWERbreathe<sup>®</sup> KH1), HR and HR variability (evaluated by Polar H7), quality of life impairment [measured by the Amyotrophic Lateral Sclerosis Assessment Questionnaire—40 items (ALSAQ-40)] and functionality [assessed by the ALS Functional Rating Scale Revised (ALSFRS-R)] were collected at baseline and after 8 weeks of intervention. We detected statistically significant differences (<i>p</i> < 0.05) with an effect size ranging from medium to large (Cohen’s <i>d</i> = 0.72–1.37); relative to the control group, the experimental group had an increased PI<sub>max</sub> (mean difference = 10.80 cm H<sub>2</sub>O; 95% CI = 3.42–18.17) and ALSFRS-R score (mean difference = 5.30 points; 95% CI = −0.03–10.63) and reduced HR (mean difference = −8.80 beats-per-minute; 95% CI = −20.27–2.67) and R-R interval (mean difference = 78.30 ms; 95% CI = 2.89–153.70). POWERbreathe<sup>®</sup> inspiratory muscle training, in addition to usual care, may improve inspiratory strength and heart rate in patients with ALS. These results encourage larger and longer trials investigating potential clinically relevant benefits of inspiratory muscle training to these patients over the disease course. |
| first_indexed | 2024-03-09T18:14:28Z |
| format | Article |
| id | doaj.art-2553af30f0ff419b9c6df3f6c546ef59 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T18:14:28Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-2553af30f0ff419b9c6df3f6c546ef592023-11-24T08:47:54ZengMDPI AGJournal of Clinical Medicine2077-03832022-11-011122665510.3390/jcm11226655POWERbreathe<sup>®</sup> Inspiratory Muscle Training in Amyotrophic Lateral SclerosisDavinia Vicente-Campos0Sandra Sanchez-Jorge1J. L. Chicharro2Ricardo Becerro-de Bengoa-Vallejo3David Rodriguez-Sanz4Arianne R. García5Marie Rivoire6Astrid Benet7Sofía Boubekeur8César Calvo-Lobo9Faculty of Health Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, SpainFaculty of Health Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, SpainGrupo FEBIO, Universidad Complutense de Madrid, 28040 Madrid, SpainFaculty of Nursing, Physical Therapy and Podiatry, Universidad Complutense de Madrid, 28040 Madrid, SpainFaculty of Nursing, Physical Therapy and Podiatry, Universidad Complutense de Madrid, 28040 Madrid, SpainFaculty of Health Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, SpainFaculty of Health Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, SpainFaculty of Health Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, SpainFaculty of Health Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, SpainFaculty of Nursing, Physical Therapy and Podiatry, Universidad Complutense de Madrid, 28040 Madrid, SpainInspiratory muscle training may benefit respiratory function, cardiocirculatory parameters, quality of life and functionality in neuromuscular diseases. This pilot study aimed to demonstrate the POWERbreathe<sup>®</sup> inspiratory muscle training effects on maximum inspiratory pressure (PI<sub>max</sub>), heart rate (HR) and HR variability, as well as the quality of life impairment and functionality in patients with Amyotrophic Lateral Sclerosis (ALS). A pilot single-blinded, non-randomized controlled clinical trial was carried out. A total of 20T ALS patients were enrolled and divided into experimental (<i>n</i> = 10) and control (<i>n</i> = 10) groups. The experimental group received POWERbreathe<sup>®</sup> inspiratory muscle training in conjunction with usual care, and the control group received only usual care for 8 weeks. PI<sub>max</sub> (measured by POWERbreathe<sup>®</sup> KH1), HR and HR variability (evaluated by Polar H7), quality of life impairment [measured by the Amyotrophic Lateral Sclerosis Assessment Questionnaire—40 items (ALSAQ-40)] and functionality [assessed by the ALS Functional Rating Scale Revised (ALSFRS-R)] were collected at baseline and after 8 weeks of intervention. We detected statistically significant differences (<i>p</i> < 0.05) with an effect size ranging from medium to large (Cohen’s <i>d</i> = 0.72–1.37); relative to the control group, the experimental group had an increased PI<sub>max</sub> (mean difference = 10.80 cm H<sub>2</sub>O; 95% CI = 3.42–18.17) and ALSFRS-R score (mean difference = 5.30 points; 95% CI = −0.03–10.63) and reduced HR (mean difference = −8.80 beats-per-minute; 95% CI = −20.27–2.67) and R-R interval (mean difference = 78.30 ms; 95% CI = 2.89–153.70). POWERbreathe<sup>®</sup> inspiratory muscle training, in addition to usual care, may improve inspiratory strength and heart rate in patients with ALS. These results encourage larger and longer trials investigating potential clinically relevant benefits of inspiratory muscle training to these patients over the disease course.https://www.mdpi.com/2077-0383/11/22/6655amyotrophic lateral sclerosisbreathing exercisesdisability evaluationheart ratemaximal respiratory pressuresquality of life |
| spellingShingle | Davinia Vicente-Campos Sandra Sanchez-Jorge J. L. Chicharro Ricardo Becerro-de Bengoa-Vallejo David Rodriguez-Sanz Arianne R. García Marie Rivoire Astrid Benet Sofía Boubekeur César Calvo-Lobo POWERbreathe<sup>®</sup> Inspiratory Muscle Training in Amyotrophic Lateral Sclerosis Journal of Clinical Medicine amyotrophic lateral sclerosis breathing exercises disability evaluation heart rate maximal respiratory pressures quality of life |
| title | POWERbreathe<sup>®</sup> Inspiratory Muscle Training in Amyotrophic Lateral Sclerosis |
| title_full | POWERbreathe<sup>®</sup> Inspiratory Muscle Training in Amyotrophic Lateral Sclerosis |
| title_fullStr | POWERbreathe<sup>®</sup> Inspiratory Muscle Training in Amyotrophic Lateral Sclerosis |
| title_full_unstemmed | POWERbreathe<sup>®</sup> Inspiratory Muscle Training in Amyotrophic Lateral Sclerosis |
| title_short | POWERbreathe<sup>®</sup> Inspiratory Muscle Training in Amyotrophic Lateral Sclerosis |
| title_sort | powerbreathe sup r sup inspiratory muscle training in amyotrophic lateral sclerosis |
| topic | amyotrophic lateral sclerosis breathing exercises disability evaluation heart rate maximal respiratory pressures quality of life |
| url | https://www.mdpi.com/2077-0383/11/22/6655 |
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