Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO<sub>2</sub>
Chemical modification of cotton-rich fabrics with TiO<sub>2</sub> nanoparticles results in photoactive self-cleaning textiles, which can provide, under UV or solar radiation, complete oxidation of low-molecular compounds, degradation of supramolecular structures, and inactivation of micr...
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MDPI AG
2022-10-01
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| author | Dmitry Selishchev Grigory Stepanov Mariia Sergeeva Maria Solovyeva Evgenii Zhuravlev Andrey Komissarov Vladimir Richter Denis Kozlov |
| author_facet | Dmitry Selishchev Grigory Stepanov Mariia Sergeeva Maria Solovyeva Evgenii Zhuravlev Andrey Komissarov Vladimir Richter Denis Kozlov |
| author_sort | Dmitry Selishchev |
| collection | DOAJ |
| description | Chemical modification of cotton-rich fabrics with TiO<sub>2</sub> nanoparticles results in photoactive self-cleaning textiles, which can provide, under UV or solar radiation, complete oxidation of low-molecular compounds, degradation of supramolecular structures, and inactivation of microorganisms due to the photocatalytic effect. In this paper, we describe, based on the example of influenza A (H1N1) virus, a photoinduced antiviral effect of cotton fabric functionalized with nanocrystalline TiO<sub>2</sub>. Fast inactivation of influenza virus occurs on the irradiated surface of photoactive fabric due to adsorption and photocatalytic degradation. The TiO<sub>2</sub> component in the prepared fabric increases the adsorption effect compared to initial cotton due to a high specific area of TiO<sub>2</sub> nanocrystallites. Long-term irradiation leads to destruction of all virion structures to the point of RNA molecules. In contrast to pristine cotton, no virus RNA is detected using the polymerase chain reaction (PCR) technique after long-term irradiation of photoactive fabric. The results of this study underline the potential of photoactive self-cleaning fabrics for application in air purification systems and personal protective clothes to provide permanent protection of people against harmful chemical and biological pollutants. |
| first_indexed | 2024-03-09T19:12:01Z |
| format | Article |
| id | doaj.art-255456727df84188897830d637e66622 |
| institution | Directory Open Access Journal |
| issn | 2073-4344 |
| language | English |
| last_indexed | 2024-03-09T19:12:01Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
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| spelling | doaj.art-255456727df84188897830d637e666222023-11-24T04:05:03ZengMDPI AGCatalysts2073-43442022-10-011211129810.3390/catal12111298Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO<sub>2</sub>Dmitry Selishchev0Grigory Stepanov1Mariia Sergeeva2Maria Solovyeva3Evgenii Zhuravlev4Andrey Komissarov5Vladimir Richter6Denis Kozlov7Research and Educational Center “Institute of Chemical Technologies”, Novosibirsk State University, Novosibirsk 630090, RussiaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk 630090, RussiaSmorodintsev Research Institute of Influenza, Ministry of Health of the Russian Federation, Saint-Petersburg 197376, RussiaResearch and Educational Center “Institute of Chemical Technologies”, Novosibirsk State University, Novosibirsk 630090, RussiaResearch and Educational Center “Institute of Chemical Technologies”, Novosibirsk State University, Novosibirsk 630090, RussiaSmorodintsev Research Institute of Influenza, Ministry of Health of the Russian Federation, Saint-Petersburg 197376, RussiaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk 630090, RussiaResearch and Educational Center “Institute of Chemical Technologies”, Novosibirsk State University, Novosibirsk 630090, RussiaChemical modification of cotton-rich fabrics with TiO<sub>2</sub> nanoparticles results in photoactive self-cleaning textiles, which can provide, under UV or solar radiation, complete oxidation of low-molecular compounds, degradation of supramolecular structures, and inactivation of microorganisms due to the photocatalytic effect. In this paper, we describe, based on the example of influenza A (H1N1) virus, a photoinduced antiviral effect of cotton fabric functionalized with nanocrystalline TiO<sub>2</sub>. Fast inactivation of influenza virus occurs on the irradiated surface of photoactive fabric due to adsorption and photocatalytic degradation. The TiO<sub>2</sub> component in the prepared fabric increases the adsorption effect compared to initial cotton due to a high specific area of TiO<sub>2</sub> nanocrystallites. Long-term irradiation leads to destruction of all virion structures to the point of RNA molecules. In contrast to pristine cotton, no virus RNA is detected using the polymerase chain reaction (PCR) technique after long-term irradiation of photoactive fabric. The results of this study underline the potential of photoactive self-cleaning fabrics for application in air purification systems and personal protective clothes to provide permanent protection of people against harmful chemical and biological pollutants.https://www.mdpi.com/2073-4344/12/11/1298TiO<sub>2</sub> photocatalystself-cleaning textilephotoactive cottoninfluenza virusantiviral propertiesRNA degradation |
| spellingShingle | Dmitry Selishchev Grigory Stepanov Mariia Sergeeva Maria Solovyeva Evgenii Zhuravlev Andrey Komissarov Vladimir Richter Denis Kozlov Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO<sub>2</sub> Catalysts TiO<sub>2</sub> photocatalyst self-cleaning textile photoactive cotton influenza virus antiviral properties RNA degradation |
| title | Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO<sub>2</sub> |
| title_full | Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO<sub>2</sub> |
| title_fullStr | Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO<sub>2</sub> |
| title_full_unstemmed | Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO<sub>2</sub> |
| title_short | Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO<sub>2</sub> |
| title_sort | inactivation and degradation of influenza a virus on the surface of photoactive self cleaning cotton fabric functionalized with nanocrystalline tio sub 2 sub |
| topic | TiO<sub>2</sub> photocatalyst self-cleaning textile photoactive cotton influenza virus antiviral properties RNA degradation |
| url | https://www.mdpi.com/2073-4344/12/11/1298 |
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