Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction—A Split-Mouth Randomized Double-Blind Clinical Trial
Aims: This study aimed to clinically evaluate of a novel gelatin-based biodegradable sponge after mandibular posterior teeth extraction to assess its abilities in controlling bleeding, pain, and dry socket compared a commercial sponge. Trial design: In this study, 26 patients who needed the extracti...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/14/4578 |
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| author | Armin Mahmoudi Mohammad Ali Ghavimi Solmaz Maleki Dizaj Simin Sharifi Seyyede Shabnam Sajjadi Amir Reza Jamei Khosroshahi |
| author_facet | Armin Mahmoudi Mohammad Ali Ghavimi Solmaz Maleki Dizaj Simin Sharifi Seyyede Shabnam Sajjadi Amir Reza Jamei Khosroshahi |
| author_sort | Armin Mahmoudi |
| collection | DOAJ |
| description | Aims: This study aimed to clinically evaluate of a novel gelatin-based biodegradable sponge after mandibular posterior teeth extraction to assess its abilities in controlling bleeding, pain, and dry socket compared a commercial sponge. Trial design: In this study, 26 patients who needed the extraction of two mandibular molar teeth were selected and, in each patient, after tooth extraction, the prepared gelatin sponge was used in the test group and the commercial sponge was used in the control group in the form of a randomized, double-blind, split-mouth clinical trial. The sterile gauzes were used on top of each sponge to absorb the extra blood (unabsorbed blood of sponges) to assess the blood absorption amount. Also, the amount of bleeding was recorded for 1 and 4 h after extraction for two groups. The amount of pain was measured for 12, 24, and 48 h after tooth extraction by Visual Analogue Scale (VAS). All patients also returned for examination four days after extraction to assess the occurrence of dry socket. Results: The results showed that the average weight of absorbed blood by sterile gauze in the control group (6.32 ± 1.06 g) was higher than in test group (3.97 ± 1.1 g), e.g., the bleeding control was better for the test group (<i>p</i> < 0.05). Bleeding was observed to be significantly reduced in the test group within 1 h (<i>p</i> = 0.003), within 1–4 h (<i>p</i> = 0.002), and after 4 h (<i>p</i> = 0.042) post-operatively in comparison to the control group. The average pain decreased significantly over time in both groups and the reduction of the pain was significantly higher for the test group (<i>p</i> < 0.05). Just one dry socket case occurred in the control group. Conclusion: The prepared sponge is recommended for use in dental surgeries because of its abilities in bleeding, pain, and dry socket control. |
| first_indexed | 2024-03-11T00:58:26Z |
| format | Article |
| id | doaj.art-25553cd5d2874bc390ddecfad6c58f60 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T00:58:26Z |
| publishDate | 2023-07-01 |
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| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-25553cd5d2874bc390ddecfad6c58f602023-11-18T19:50:50ZengMDPI AGJournal of Clinical Medicine2077-03832023-07-011214457810.3390/jcm12144578Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction—A Split-Mouth Randomized Double-Blind Clinical TrialArmin Mahmoudi0Mohammad Ali Ghavimi1Solmaz Maleki Dizaj2Simin Sharifi3Seyyede Shabnam Sajjadi4Amir Reza Jamei Khosroshahi5Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 51548-53431, IranDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 51548-53431, IranDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 51548-53431, IranDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 51548-53431, IranDepartment of Pediatric Dentistry, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 51548-53431, IranDepartment of Pediatric Dentistry, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 51548-53431, IranAims: This study aimed to clinically evaluate of a novel gelatin-based biodegradable sponge after mandibular posterior teeth extraction to assess its abilities in controlling bleeding, pain, and dry socket compared a commercial sponge. Trial design: In this study, 26 patients who needed the extraction of two mandibular molar teeth were selected and, in each patient, after tooth extraction, the prepared gelatin sponge was used in the test group and the commercial sponge was used in the control group in the form of a randomized, double-blind, split-mouth clinical trial. The sterile gauzes were used on top of each sponge to absorb the extra blood (unabsorbed blood of sponges) to assess the blood absorption amount. Also, the amount of bleeding was recorded for 1 and 4 h after extraction for two groups. The amount of pain was measured for 12, 24, and 48 h after tooth extraction by Visual Analogue Scale (VAS). All patients also returned for examination four days after extraction to assess the occurrence of dry socket. Results: The results showed that the average weight of absorbed blood by sterile gauze in the control group (6.32 ± 1.06 g) was higher than in test group (3.97 ± 1.1 g), e.g., the bleeding control was better for the test group (<i>p</i> < 0.05). Bleeding was observed to be significantly reduced in the test group within 1 h (<i>p</i> = 0.003), within 1–4 h (<i>p</i> = 0.002), and after 4 h (<i>p</i> = 0.042) post-operatively in comparison to the control group. The average pain decreased significantly over time in both groups and the reduction of the pain was significantly higher for the test group (<i>p</i> < 0.05). Just one dry socket case occurred in the control group. Conclusion: The prepared sponge is recommended for use in dental surgeries because of its abilities in bleeding, pain, and dry socket control.https://www.mdpi.com/2077-0383/12/14/4578gelatinspongehemostaticpaindry socketrandomized |
| spellingShingle | Armin Mahmoudi Mohammad Ali Ghavimi Solmaz Maleki Dizaj Simin Sharifi Seyyede Shabnam Sajjadi Amir Reza Jamei Khosroshahi Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction—A Split-Mouth Randomized Double-Blind Clinical Trial Journal of Clinical Medicine gelatin sponge hemostatic pain dry socket randomized |
| title | Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction—A Split-Mouth Randomized Double-Blind Clinical Trial |
| title_full | Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction—A Split-Mouth Randomized Double-Blind Clinical Trial |
| title_fullStr | Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction—A Split-Mouth Randomized Double-Blind Clinical Trial |
| title_full_unstemmed | Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction—A Split-Mouth Randomized Double-Blind Clinical Trial |
| title_short | Efficacy of a New Hemostatic Dental Sponge in Controlling Bleeding, Pain, and Dry Socket Following Mandibular Posterior Teeth Extraction—A Split-Mouth Randomized Double-Blind Clinical Trial |
| title_sort | efficacy of a new hemostatic dental sponge in controlling bleeding pain and dry socket following mandibular posterior teeth extraction a split mouth randomized double blind clinical trial |
| topic | gelatin sponge hemostatic pain dry socket randomized |
| url | https://www.mdpi.com/2077-0383/12/14/4578 |
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