Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis
Aim: To compare 3D steady-state free-precession (SSFP) non-contrast magnetic resonance angiography (NC-MRA) with contrast-enhanced MRA (CE-MRA) for quantitative and qualitative analysis of thoracic arteries in pediatric patients with congenital heart disease. Methodology: Forty patients with thoraci...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2018-09-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0378603X18300627 |
| _version_ | 1818217630482300928 |
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| author | Wessam Abdelrahman Elzayat Marwa M. Onsy Mohamed Talaat Ali Hassan Ali El-Kiki Rania Ali Hegazy |
| author_facet | Wessam Abdelrahman Elzayat Marwa M. Onsy Mohamed Talaat Ali Hassan Ali El-Kiki Rania Ali Hegazy |
| author_sort | Wessam Abdelrahman Elzayat |
| collection | DOAJ |
| description | Aim: To compare 3D steady-state free-precession (SSFP) non-contrast magnetic resonance angiography (NC-MRA) with contrast-enhanced MRA (CE-MRA) for quantitative and qualitative analysis of thoracic arteries in pediatric patients with congenital heart disease. Methodology: Forty patients with thoracic vascular anomalies (22 boys & 18 girls) ranging in age between 6 months and 14 years (mean age 4.58 ± 4.5) were included in this prospective study. Measurements of the thoracic arteries were taken by 3D SSFP NC-MRA & CE-MRA. Image quality was assessed using a four-point score. Pearson's and Spearman's Correlation Coefficients were calculated for correlation analysis while Student's t and Mann-Whitney U tests were used for comparative analysis, Bland-Altman plots were employed to demonstrate the level of agreement between the 2 techniques. Results: Measurements from NC-CMRA images were comparable to those from CE-MRA. All measures highly correlated (r > 0.9), 3D SSFP NC-MRA exhibited a significantly higher image quality score than contrast- enhanced MRA, the mean difference was significantly lower than that of the 3D SSFP; (p-value <0.0001). Conclusion: NC-MRA produced similar and comparable measurements of the thoracic arteries with superior image quality when compared to contrast- enhanced MRA in pediatric congenital heart defects. Keywords: MRI, Thoracic vessels, Congenital heart |
| first_indexed | 2024-12-12T07:10:55Z |
| format | Article |
| id | doaj.art-25555b48a95245569aef67a0a4eacabd |
| institution | Directory Open Access Journal |
| issn | 0378-603X |
| language | English |
| last_indexed | 2024-12-12T07:10:55Z |
| publishDate | 2018-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-25555b48a95245569aef67a0a4eacabd2022-12-22T00:33:37ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2018-09-01493747754Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysisWessam Abdelrahman Elzayat0Marwa M. Onsy1Mohamed Talaat Ali2Hassan Ali El-Kiki3Rania Ali Hegazy4Diagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, Cairo, Egypt; Corresponding author at: Diagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, El-Manial, 11956 Cairo, Egypt.Diagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, Cairo, EgyptDiagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, Cairo, EgyptDiagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, Cairo, EgyptPediatric Department, Abu El Reesh Hospital, Kasr Al-Ainy, Cairo, EgyptAim: To compare 3D steady-state free-precession (SSFP) non-contrast magnetic resonance angiography (NC-MRA) with contrast-enhanced MRA (CE-MRA) for quantitative and qualitative analysis of thoracic arteries in pediatric patients with congenital heart disease. Methodology: Forty patients with thoracic vascular anomalies (22 boys & 18 girls) ranging in age between 6 months and 14 years (mean age 4.58 ± 4.5) were included in this prospective study. Measurements of the thoracic arteries were taken by 3D SSFP NC-MRA & CE-MRA. Image quality was assessed using a four-point score. Pearson's and Spearman's Correlation Coefficients were calculated for correlation analysis while Student's t and Mann-Whitney U tests were used for comparative analysis, Bland-Altman plots were employed to demonstrate the level of agreement between the 2 techniques. Results: Measurements from NC-CMRA images were comparable to those from CE-MRA. All measures highly correlated (r > 0.9), 3D SSFP NC-MRA exhibited a significantly higher image quality score than contrast- enhanced MRA, the mean difference was significantly lower than that of the 3D SSFP; (p-value <0.0001). Conclusion: NC-MRA produced similar and comparable measurements of the thoracic arteries with superior image quality when compared to contrast- enhanced MRA in pediatric congenital heart defects. Keywords: MRI, Thoracic vessels, Congenital hearthttp://www.sciencedirect.com/science/article/pii/S0378603X18300627 |
| spellingShingle | Wessam Abdelrahman Elzayat Marwa M. Onsy Mohamed Talaat Ali Hassan Ali El-Kiki Rania Ali Hegazy Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis The Egyptian Journal of Radiology and Nuclear Medicine |
| title | Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
| title_full | Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
| title_fullStr | Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
| title_full_unstemmed | Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
| title_short | Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
| title_sort | non contrast versus contrast enhanced mri of the great thoracic vessels in pediatric congenital heart disease a quantitative and qualitative analysis |
| url | http://www.sciencedirect.com/science/article/pii/S0378603X18300627 |
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