Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review
The skin is the largest and outermost organ of the human body. The microbial diversity of the skin can be influenced by several variable factors such as physiological state, lifestyle, and geographical locations. Recent years have seen increased interest in research aiming at an improved understandi...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-09-01
|
| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/12/9/1420 |
| _version_ | 1797485670765166592 |
|---|---|
| author | Esther Olunoiki Jacqueline Rehner Markus Bischoff Elena Koshel Thomas Vogt Jörg Reichrath Sören L. Becker |
| author_facet | Esther Olunoiki Jacqueline Rehner Markus Bischoff Elena Koshel Thomas Vogt Jörg Reichrath Sören L. Becker |
| author_sort | Esther Olunoiki |
| collection | DOAJ |
| description | The skin is the largest and outermost organ of the human body. The microbial diversity of the skin can be influenced by several variable factors such as physiological state, lifestyle, and geographical locations. Recent years have seen increased interest in research aiming at an improved understanding of the relationship between the human microbiota and several diseases. Albeit understudied, interesting correlations between the skin microbiota and several dermatological conditions have been observed. Studies have shown that a decrease or increase in the abundance of certain microbial communities can be implicated in several dermatological pathologies. This narrative review (i) examines the role of the skin microbiota in the maintenance of skin homeostasis and health, (ii) provides examples on how some common skin diseases (acne inversa, candidiasis, psoriasis) are associated with the dysbiosis of microbial communities, and (iii) describes how recent research approaches used in skin microbiome studies may lead to improved, more sensitive diagnostics and individual therapeutics in the foreseeable future. |
| first_indexed | 2024-03-09T23:22:10Z |
| format | Article |
| id | doaj.art-255869d10fe74c39b818863967898c75 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T23:22:10Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-255869d10fe74c39b818863967898c752023-11-23T17:23:49ZengMDPI AGLife2075-17292022-09-01129142010.3390/life12091420Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative ReviewEsther Olunoiki0Jacqueline Rehner1Markus Bischoff2Elena Koshel3Thomas Vogt4Jörg Reichrath5Sören L. Becker6Institute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, GermanyInstitute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, GermanyInstitute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, Germany“Solution Chemistry of Advanced Materials and Technologies” (SCAMT) Institute, ITMO University, 191002 St. Petersburg, RussiaDepartment of Dermatology, Venereology, Allergology, Saarland University Medical Center, 66421 Homburg, GermanyDepartment of Dermatology, Venereology, Allergology, Saarland University Medical Center, 66421 Homburg, GermanyInstitute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, GermanyThe skin is the largest and outermost organ of the human body. The microbial diversity of the skin can be influenced by several variable factors such as physiological state, lifestyle, and geographical locations. Recent years have seen increased interest in research aiming at an improved understanding of the relationship between the human microbiota and several diseases. Albeit understudied, interesting correlations between the skin microbiota and several dermatological conditions have been observed. Studies have shown that a decrease or increase in the abundance of certain microbial communities can be implicated in several dermatological pathologies. This narrative review (i) examines the role of the skin microbiota in the maintenance of skin homeostasis and health, (ii) provides examples on how some common skin diseases (acne inversa, candidiasis, psoriasis) are associated with the dysbiosis of microbial communities, and (iii) describes how recent research approaches used in skin microbiome studies may lead to improved, more sensitive diagnostics and individual therapeutics in the foreseeable future.https://www.mdpi.com/2075-1729/12/9/1420dermatologyhuman microbiomemetagenomicsmicrobial diversitypsoriasiscandidiasis |
| spellingShingle | Esther Olunoiki Jacqueline Rehner Markus Bischoff Elena Koshel Thomas Vogt Jörg Reichrath Sören L. Becker Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review Life dermatology human microbiome metagenomics microbial diversity psoriasis candidiasis |
| title | Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review |
| title_full | Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review |
| title_fullStr | Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review |
| title_full_unstemmed | Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review |
| title_short | Characteristics of the Skin Microbiome in Selected Dermatological Conditions: A Narrative Review |
| title_sort | characteristics of the skin microbiome in selected dermatological conditions a narrative review |
| topic | dermatology human microbiome metagenomics microbial diversity psoriasis candidiasis |
| url | https://www.mdpi.com/2075-1729/12/9/1420 |
| work_keys_str_mv | AT estherolunoiki characteristicsoftheskinmicrobiomeinselecteddermatologicalconditionsanarrativereview AT jacquelinerehner characteristicsoftheskinmicrobiomeinselecteddermatologicalconditionsanarrativereview AT markusbischoff characteristicsoftheskinmicrobiomeinselecteddermatologicalconditionsanarrativereview AT elenakoshel characteristicsoftheskinmicrobiomeinselecteddermatologicalconditionsanarrativereview AT thomasvogt characteristicsoftheskinmicrobiomeinselecteddermatologicalconditionsanarrativereview AT jorgreichrath characteristicsoftheskinmicrobiomeinselecteddermatologicalconditionsanarrativereview AT sorenlbecker characteristicsoftheskinmicrobiomeinselecteddermatologicalconditionsanarrativereview |