Analysis of inpatient care for HIV-positive patients with malignant lymphomas and hepatitis over 5 years (2011—2015) at the A.S.Loginov Moscow Clinical Research Center, Moscow Healthcare Department

The authors give their own data in the first Russian publication on 170 patients with lymphomas and hepatitis concurrent with HIV infection, on the distribution of therapy regimens by nosological entities and the number of deaths. Conventional protocols and programs were used for diagnosis and treat...

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Main Authors: A V Pivnik, M V Tumanova, A V Chistyakova, G A Dudina, M G Dubnitskaya, O V Mukhin, E P Sergeeva
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2017-07-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/32314/pdf
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author A V Pivnik
M V Tumanova
A V Chistyakova
G A Dudina
M G Dubnitskaya
O V Mukhin
E P Sergeeva
author_facet A V Pivnik
M V Tumanova
A V Chistyakova
G A Dudina
M G Dubnitskaya
O V Mukhin
E P Sergeeva
author_sort A V Pivnik
collection DOAJ
description The authors give their own data in the first Russian publication on 170 patients with lymphomas and hepatitis concurrent with HIV infection, on the distribution of therapy regimens by nosological entities and the number of deaths. Conventional protocols and programs were used for diagnosis and treatment. All the patients received highly active antiretroviral therapy. Lymphoma was treated according to the conventional programs using rituximab in people without hepatitis B. Aggressive lymphomas, such as diffuse large B-cell lymphoma, Burkitt lymphoma, and plasmablastic lymphoma, were identified in most patients. Hodgkin’s lymphoma is the matter of a separate study; it differs in its pathogenesis from other lymphomas. The rate of coinfection with hepatitis was high in the entire group of patients with lymphomas. The major prognostic indicators included low CD4 T-cell counts (less than 50), stage IVB lymphoma, and hepatitis. Complete remissions were achieved in 40% of patients. Forty-one (24%) patients died.
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spelling doaj.art-2559bfc4fa114c519ee3e0484c11a00b2022-12-21T19:00:00Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422017-07-0189710511110.17116/terarkh2017897105-11129314Analysis of inpatient care for HIV-positive patients with malignant lymphomas and hepatitis over 5 years (2011—2015) at the A.S.Loginov Moscow Clinical Research Center, Moscow Healthcare DepartmentA V PivnikM V TumanovaA V ChistyakovaG A DudinaM G DubnitskayaO V MukhinE P SergeevaThe authors give their own data in the first Russian publication on 170 patients with lymphomas and hepatitis concurrent with HIV infection, on the distribution of therapy regimens by nosological entities and the number of deaths. Conventional protocols and programs were used for diagnosis and treatment. All the patients received highly active antiretroviral therapy. Lymphoma was treated according to the conventional programs using rituximab in people without hepatitis B. Aggressive lymphomas, such as diffuse large B-cell lymphoma, Burkitt lymphoma, and plasmablastic lymphoma, were identified in most patients. Hodgkin’s lymphoma is the matter of a separate study; it differs in its pathogenesis from other lymphomas. The rate of coinfection with hepatitis was high in the entire group of patients with lymphomas. The major prognostic indicators included low CD4 T-cell counts (less than 50), stage IVB lymphoma, and hepatitis. Complete remissions were achieved in 40% of patients. Forty-one (24%) patients died.https://ter-arkhiv.ru/0040-3660/article/viewFile/32314/pdfhiv infectionaggressive lymphomashepatitis
spellingShingle A V Pivnik
M V Tumanova
A V Chistyakova
G A Dudina
M G Dubnitskaya
O V Mukhin
E P Sergeeva
Analysis of inpatient care for HIV-positive patients with malignant lymphomas and hepatitis over 5 years (2011—2015) at the A.S.Loginov Moscow Clinical Research Center, Moscow Healthcare Department
Терапевтический архив
hiv infection
aggressive lymphomas
hepatitis
title Analysis of inpatient care for HIV-positive patients with malignant lymphomas and hepatitis over 5 years (2011—2015) at the A.S.Loginov Moscow Clinical Research Center, Moscow Healthcare Department
title_full Analysis of inpatient care for HIV-positive patients with malignant lymphomas and hepatitis over 5 years (2011—2015) at the A.S.Loginov Moscow Clinical Research Center, Moscow Healthcare Department
title_fullStr Analysis of inpatient care for HIV-positive patients with malignant lymphomas and hepatitis over 5 years (2011—2015) at the A.S.Loginov Moscow Clinical Research Center, Moscow Healthcare Department
title_full_unstemmed Analysis of inpatient care for HIV-positive patients with malignant lymphomas and hepatitis over 5 years (2011—2015) at the A.S.Loginov Moscow Clinical Research Center, Moscow Healthcare Department
title_short Analysis of inpatient care for HIV-positive patients with malignant lymphomas and hepatitis over 5 years (2011—2015) at the A.S.Loginov Moscow Clinical Research Center, Moscow Healthcare Department
title_sort analysis of inpatient care for hiv positive patients with malignant lymphomas and hepatitis over 5 years 2011 2015 at the a s loginov moscow clinical research center moscow healthcare department
topic hiv infection
aggressive lymphomas
hepatitis
url https://ter-arkhiv.ru/0040-3660/article/viewFile/32314/pdf
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