CTLA4 Methylation and its Expression as a Prognostic Biomarker in Tobacco Users with and without Oral Squamous Cell Carcinoma- A Protocol for Cross-sectional Study

Introduction: Oral Squamous Cell Carcinoma (OSCC) is characterised by immunosuppression mediated by evasion of ‘immune checkpoints’ by tumour cells. Cytotoxic T Lymphocyte Associated Protein 4 (CTLA4) is one of the immune checkpoint molecule whose role in oral carcinogenesis remains to be elucidated...

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Bibliographic Details
Main Authors: Prajakta R Zade, Minal S Chaudhary, Muhil V Seralathan, Alka H Hande, Madhuri N Gawande
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2023-04-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/17799/59285_CE[Ra1]_F(IS)_PF1(DA_KM)_PN(KM).pdf