Impact of retrieved lymph node count on short-term complications in patients with gastric cancer
Abstract Background It is well established that retrieved lymph node (RLN) counts were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLN count and short-term complications after radical surgery. Methods A total of 1487 c...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-08-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12957-020-02000-9 |
| _version_ | 1828894893239435264 |
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| author | Feng Sun Song Liu Peng Song Chen Zhang Zhijian Liu Wenxian Guan Meng Wang |
| author_facet | Feng Sun Song Liu Peng Song Chen Zhang Zhijian Liu Wenxian Guan Meng Wang |
| author_sort | Feng Sun |
| collection | DOAJ |
| description | Abstract Background It is well established that retrieved lymph node (RLN) counts were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLN count and short-term complications after radical surgery. Methods A total of 1487 consecutive GC patients between January 2016 and December 2018 at Nanjing Drum Tower Hospital were retrospectively analyzed. Univariate analyses were performed to elucidate the association between RLN count and postoperative complications. We further identified clinical factors that might affect the RLN count. Results Among all of the patients, postoperative complications occurred in 435 (29.3%) patients. The mean RLN count was 25.1, and 864 (58.1%) patients were diagnosed with lymph node metastasis. Univariate analyses showed no significant difference between RLN count and postoperative complications (both overall and stratified by CDC grade). Univariate and multivariate analyses further revealed that type of resection, tumor invasion, and lymph node metastasis were associated with RLN count. Conclusions The current study demonstrated that RLN count was not associated with postoperative short-term complications following gastrectomy of GC, which provided a rationale for the determination of a proper RLN count of curative gastrectomy. |
| first_indexed | 2024-12-13T14:19:40Z |
| format | Article |
| id | doaj.art-25617e4bc7a64926892b86febd541a3a |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-13T14:19:40Z |
| publishDate | 2020-08-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-25617e4bc7a64926892b86febd541a3a2022-12-21T23:42:08ZengBMCWorld Journal of Surgical Oncology1477-78192020-08-011811710.1186/s12957-020-02000-9Impact of retrieved lymph node count on short-term complications in patients with gastric cancerFeng Sun0Song Liu1Peng Song2Chen Zhang3Zhijian Liu4Wenxian Guan5Meng Wang6Department of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical SchoolDepartment of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical SchoolDepartment of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical SchoolDepartment of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical SchoolDepartment of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical SchoolDepartment of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical SchoolDepartment of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical SchoolAbstract Background It is well established that retrieved lymph node (RLN) counts were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLN count and short-term complications after radical surgery. Methods A total of 1487 consecutive GC patients between January 2016 and December 2018 at Nanjing Drum Tower Hospital were retrospectively analyzed. Univariate analyses were performed to elucidate the association between RLN count and postoperative complications. We further identified clinical factors that might affect the RLN count. Results Among all of the patients, postoperative complications occurred in 435 (29.3%) patients. The mean RLN count was 25.1, and 864 (58.1%) patients were diagnosed with lymph node metastasis. Univariate analyses showed no significant difference between RLN count and postoperative complications (both overall and stratified by CDC grade). Univariate and multivariate analyses further revealed that type of resection, tumor invasion, and lymph node metastasis were associated with RLN count. Conclusions The current study demonstrated that RLN count was not associated with postoperative short-term complications following gastrectomy of GC, which provided a rationale for the determination of a proper RLN count of curative gastrectomy.http://link.springer.com/article/10.1186/s12957-020-02000-9Retrieved lymph nodesPostoperative complicationsGastric cancer |
| spellingShingle | Feng Sun Song Liu Peng Song Chen Zhang Zhijian Liu Wenxian Guan Meng Wang Impact of retrieved lymph node count on short-term complications in patients with gastric cancer World Journal of Surgical Oncology Retrieved lymph nodes Postoperative complications Gastric cancer |
| title | Impact of retrieved lymph node count on short-term complications in patients with gastric cancer |
| title_full | Impact of retrieved lymph node count on short-term complications in patients with gastric cancer |
| title_fullStr | Impact of retrieved lymph node count on short-term complications in patients with gastric cancer |
| title_full_unstemmed | Impact of retrieved lymph node count on short-term complications in patients with gastric cancer |
| title_short | Impact of retrieved lymph node count on short-term complications in patients with gastric cancer |
| title_sort | impact of retrieved lymph node count on short term complications in patients with gastric cancer |
| topic | Retrieved lymph nodes Postoperative complications Gastric cancer |
| url | http://link.springer.com/article/10.1186/s12957-020-02000-9 |
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