Relationship between Maternal Serum Copper Level and Birth Weight Neonate

Background and Objectives: Low birth weight (LBW) is a major public health problem. LBW is associated with increased neonatal morbidity and mortality. There is no consensus in the literature as to whether maternal copper nutrition is associated with pregnancy outcome or fetal growth. Methods: This c...

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Main Authors: Mirzarahimi M, Saadati H, Enteshari A, Mazani M, Shahizadeh S
Format: Article
Language:fas
Published: Qom University of Medical Sciences 2012-01-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Subjects:
Online Access:http://journal.muq.ac.ir/library/upload/article/af_2256734733557954267532346965969922234252_jmsQZB11U6E5Z.pdf
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author Mirzarahimi M
Saadati H
Enteshari A
Mazani M
Shahizadeh S
author_facet Mirzarahimi M
Saadati H
Enteshari A
Mazani M
Shahizadeh S
author_sort Mirzarahimi M
collection DOAJ
description Background and Objectives: Low birth weight (LBW) is a major public health problem. LBW is associated with increased neonatal morbidity and mortality. There is no consensus in the literature as to whether maternal copper nutrition is associated with pregnancy outcome or fetal growth. Methods: This case-control study was carried out at Alavi Hospital in Ardabil between August 2008 and August 2009. 56 women who had delivered low-birth- weight infants (<2500gr) were taken as the case group, and from the mothers who had delivered normal birth weight infants (≥2500gr), 56 were selected at random as the control group. Venous blood samples were obtained from the mothers. Serum zinc level was determined by the Atomic Absorption Spectrophotometer method.Results: Mean of birth weight in infants, maternal age, body mass index in mothers and socioeconomic or demographic factors did not differ between cases and control groups. Maternal copper concentration (μg/dl) differed between Cases and Controls; 231.75±38.12μg/dl vs. 204.42±31.30μg/dl respectively. There is a significant difference (p<0.001) in the serum copper concentration between the two groups.Conclusion: There is a negative relation between low infant birth weight and maternal copper concentration.
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spelling doaj.art-256183eaa78b4dce8ed4e780628b59a72022-12-22T01:39:04ZfasQom University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum1735-77992008-13752012-01-01541114Relationship between Maternal Serum Copper Level and Birth Weight NeonateMirzarahimi MSaadati HEnteshari AMazani MShahizadeh SBackground and Objectives: Low birth weight (LBW) is a major public health problem. LBW is associated with increased neonatal morbidity and mortality. There is no consensus in the literature as to whether maternal copper nutrition is associated with pregnancy outcome or fetal growth. Methods: This case-control study was carried out at Alavi Hospital in Ardabil between August 2008 and August 2009. 56 women who had delivered low-birth- weight infants (<2500gr) were taken as the case group, and from the mothers who had delivered normal birth weight infants (≥2500gr), 56 were selected at random as the control group. Venous blood samples were obtained from the mothers. Serum zinc level was determined by the Atomic Absorption Spectrophotometer method.Results: Mean of birth weight in infants, maternal age, body mass index in mothers and socioeconomic or demographic factors did not differ between cases and control groups. Maternal copper concentration (μg/dl) differed between Cases and Controls; 231.75±38.12μg/dl vs. 204.42±31.30μg/dl respectively. There is a significant difference (p<0.001) in the serum copper concentration between the two groups.Conclusion: There is a negative relation between low infant birth weight and maternal copper concentration.http://journal.muq.ac.ir/library/upload/article/af_2256734733557954267532346965969922234252_jmsQZB11U6E5Z.pdfCopperInfantLow Birth WeightSpectrophotometerAtomic
spellingShingle Mirzarahimi M
Saadati H
Enteshari A
Mazani M
Shahizadeh S
Relationship between Maternal Serum Copper Level and Birth Weight Neonate
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Copper
Infant
Low Birth Weight
Spectrophotometer
Atomic
title Relationship between Maternal Serum Copper Level and Birth Weight Neonate
title_full Relationship between Maternal Serum Copper Level and Birth Weight Neonate
title_fullStr Relationship between Maternal Serum Copper Level and Birth Weight Neonate
title_full_unstemmed Relationship between Maternal Serum Copper Level and Birth Weight Neonate
title_short Relationship between Maternal Serum Copper Level and Birth Weight Neonate
title_sort relationship between maternal serum copper level and birth weight neonate
topic Copper
Infant
Low Birth Weight
Spectrophotometer
Atomic
url http://journal.muq.ac.ir/library/upload/article/af_2256734733557954267532346965969922234252_jmsQZB11U6E5Z.pdf
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