Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis
Background: The diagnosis of osteomyelitis is invasive and expensive as the current standard technique is the bone biopsy. Our aim was to compare the degree of agreement and concordance between standard bone biopsy and other non-bone techniques. Methods: We performed an electronic search through 12...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-11-01
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| Series: | Journal of Infection and Public Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034120306316 |
| _version_ | 1819150874493059072 |
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| author | Gehad Mohamed Tawfik Mahmoud Dibas Nguyen Minh Dung Ahmad Awad Alkhebairy Mona Hanafy Mahmoud Mohamed Hosny Ibrahim Nada Ramadan Abd Elhady Ahmed M. Sayed Ahmed Samir Gehad Ahmed Saber Abdelrahman Muhammed Khaled Elfaituri Nguyen Hai Nam Amr Ehab El-Qushayri Nguyen Tien Huy |
| author_facet | Gehad Mohamed Tawfik Mahmoud Dibas Nguyen Minh Dung Ahmad Awad Alkhebairy Mona Hanafy Mahmoud Mohamed Hosny Ibrahim Nada Ramadan Abd Elhady Ahmed M. Sayed Ahmed Samir Gehad Ahmed Saber Abdelrahman Muhammed Khaled Elfaituri Nguyen Hai Nam Amr Ehab El-Qushayri Nguyen Tien Huy |
| author_sort | Gehad Mohamed Tawfik |
| collection | DOAJ |
| description | Background: The diagnosis of osteomyelitis is invasive and expensive as the current standard technique is the bone biopsy. Our aim was to compare the degree of agreement and concordance between standard bone biopsy and other non-bone techniques. Methods: We performed an electronic search through 12 electronic databases to retrieve relevant studeis. Our criteria included any original article that reported the degree of agreement and/or the concordance between bone biopsy and other non-bone techniques in diagnosing osteomyelitis. We published our protocol in PROSPERO with a registration number, CRD42017080336. Results: There were 29 studies included in the qualitative analysis, of which 15 studies were included in the meta-analysis. Samples from sinus tract had the highest concordance with bone biopsy samples, while swab samples were the least concordant with bone biopsy samples. Additionally, Staphylococcus aureus was the most common bacteria isolated and the most concordant from samples, compared to other types of causative agents. Sinus tract had a significantly very high degree of agreement with bone samples. S. aureus had the highest degree of agreement in bone smaples. Conclusion: Diagnosis of osteomyelitis using sinus tract swab is close in results’ accuracy to bone biopsy. S. aureus was the most common extracted organism found in these samples and had the highest degree of agreement. |
| first_indexed | 2024-12-22T14:24:26Z |
| format | Article |
| id | doaj.art-2562c8223dcf46e48a44f4460d0b9a1d |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-12-22T14:24:26Z |
| publishDate | 2020-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-2562c8223dcf46e48a44f4460d0b9a1d2022-12-21T18:22:54ZengElsevierJournal of Infection and Public Health1876-03412020-11-01131116821693Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysisGehad Mohamed Tawfik0Mahmoud Dibas1Nguyen Minh Dung2Ahmad Awad Alkhebairy3Mona Hanafy Mahmoud4Mohamed Hosny Ibrahim5Nada Ramadan Abd Elhady6Ahmed M. Sayed7Ahmed Samir Gehad8Ahmed Saber Abdelrahman9Muhammed Khaled Elfaituri10Nguyen Hai Nam11Amr Ehab El-Qushayri12Nguyen Tien Huy13Faculty of Medicine, Ain Shams University, Cairo, Egypt; Online Research Club (www.onlineresearchclub.org)Online Research Club (www.onlineresearchclub.org); Sulaiman Al Rajhi Colleges, College of Medicine, Saudi ArabiaOnline Research Club (www.onlineresearchclub.org); Department of Sport Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, 70000, Viet NamOnline Research Club (www.onlineresearchclub.org); Faculty of Medicine, Al-Azhar University, Cairo, EgyptFaculty of Medicine, Ain Shams University, Cairo, Egypt; Online Research Club (www.onlineresearchclub.org)Faculty of Medicine, Ain Shams University, Cairo, Egypt; Online Research Club (www.onlineresearchclub.org)Online Research Club (www.onlineresearchclub.org); Faculty of Medicine, Fayoum University, Fayoum, EgyptOnline Research Club (www.onlineresearchclub.org); Faculty of Pharmacy, Al-Azhar University, Cairo, EgyptOnline Research Club (www.onlineresearchclub.org); Faculty of Medicine, Zagazig University, Zagazig, EgyptOnline Research Club (www.onlineresearchclub.org); Faculty of Medicine, Misr University for Science and Technology, Giza, EgyptOnline Research Club (www.onlineresearchclub.org); Faculty of Medicine, University of Tripoli, Tripoli, LibyaOnline Research Club (www.onlineresearchclub.org); Department of General Surgery, University of Medicine and Pharmacy at Ho Chi Minh City, 70000, Viet NamOnline Research Club (www.onlineresearchclub.org); Faculty of Medicine, Minia University, Minia, 61519, EgyptEvidence Based Medicine Research Group, Ton Duc Thang University, Ho Chi Minh City, 70000, Viet Nam; Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, 70000, Viet Nam; Corresponding author at: Evidence Based Medicine Research Group & Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Viet Nam.Background: The diagnosis of osteomyelitis is invasive and expensive as the current standard technique is the bone biopsy. Our aim was to compare the degree of agreement and concordance between standard bone biopsy and other non-bone techniques. Methods: We performed an electronic search through 12 electronic databases to retrieve relevant studeis. Our criteria included any original article that reported the degree of agreement and/or the concordance between bone biopsy and other non-bone techniques in diagnosing osteomyelitis. We published our protocol in PROSPERO with a registration number, CRD42017080336. Results: There were 29 studies included in the qualitative analysis, of which 15 studies were included in the meta-analysis. Samples from sinus tract had the highest concordance with bone biopsy samples, while swab samples were the least concordant with bone biopsy samples. Additionally, Staphylococcus aureus was the most common bacteria isolated and the most concordant from samples, compared to other types of causative agents. Sinus tract had a significantly very high degree of agreement with bone samples. S. aureus had the highest degree of agreement in bone smaples. Conclusion: Diagnosis of osteomyelitis using sinus tract swab is close in results’ accuracy to bone biopsy. S. aureus was the most common extracted organism found in these samples and had the highest degree of agreement.http://www.sciencedirect.com/science/article/pii/S1876034120306316OsteomyelitisDiagnosisBone biopsySwabConcordance |
| spellingShingle | Gehad Mohamed Tawfik Mahmoud Dibas Nguyen Minh Dung Ahmad Awad Alkhebairy Mona Hanafy Mahmoud Mohamed Hosny Ibrahim Nada Ramadan Abd Elhady Ahmed M. Sayed Ahmed Samir Gehad Ahmed Saber Abdelrahman Muhammed Khaled Elfaituri Nguyen Hai Nam Amr Ehab El-Qushayri Nguyen Tien Huy Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis Journal of Infection and Public Health Osteomyelitis Diagnosis Bone biopsy Swab Concordance |
| title | Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis |
| title_full | Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis |
| title_fullStr | Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis |
| title_full_unstemmed | Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis |
| title_short | Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis |
| title_sort | concordance of bone and non bone specimens in microbiological diagnosis of osteomyelitis a systematic review and meta analysis |
| topic | Osteomyelitis Diagnosis Bone biopsy Swab Concordance |
| url | http://www.sciencedirect.com/science/article/pii/S1876034120306316 |
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