<i>MOSR</i> and <i>NDH</i>A Genes Comprising G-Quadruplex as Promising Therapeutic Targets against <i>Mycobacterium tuberculosis</i>: Molecular Recognition by Mitoxantrone Suppresses Replication and Gene Regulation

<i>MOSR</i> and <i>NDH</i>A Genes Comprising G-Quadruplex as Promising Therapeutic Targets against <i>Mycobacterium tuberculosis</i>: Molecular Recognition by Mitoxantrone Suppresses Replication and Gene Regulation

Occurrence of non-canonical G-quadruplex (G4) DNA structures in the genome have been recognized as key factors in gene regulation and several other cellular processes. The <i>mosR</i> and <i>ndhA genes</i> involved in pathways of oxidation sensing regulation and ATP generatio...

Full description

Bibliographic Details
Main Authors: Arpita Dey, Kushi Anand, Amit Singh, Ramasare Prasad, Ritu Barthwal
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Genes
Subjects:
G-quadruplex
<i>mosR</i>/<i>ndhA</i> genes
downregulation
DNA replication
DNA targeting by mitoxantrone
spectroscopy and calorimetry
Online Access:https://www.mdpi.com/2073-4425/14/5/978

Internet

https://www.mdpi.com/2073-4425/14/5/978

Similar Items