Current status of endoscopic balloon dilation for Crohn's disease
The therapeutic target in Crohn's disease (CD) has been raised to the achievement of mucosal healing. Although effective treatments that target cytokines and other molecules has been widely used for CD, intestinal strictures are still a major cause of surgery. Endoscopic balloon dilation (EBD)...
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| Format: | Article |
| Language: | English |
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Korean Association for the Study of Intestinal Diseases
2017-04-01
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| Series: | Intestinal Research |
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| Online Access: | https://doi.org/10.5217/ir.2017.15.2.166 |
| _version_ | 1819076792479121408 |
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| author | Fumihito Hirai |
| author_facet | Fumihito Hirai |
| author_sort | Fumihito Hirai |
| collection | DOAJ |
| description | The therapeutic target in Crohn's disease (CD) has been raised to the achievement of mucosal healing. Although effective treatments that target cytokines and other molecules has been widely used for CD, intestinal strictures are still a major cause of surgery. Endoscopic balloon dilation (EBD) is known to be an effective and safe intervention for intestinal strictures in CD. Since frequent intestinal resection often results in short bowel syndrome and can decrease the quality of life, EBD can help avoid surgery. EBD with a conventional colonoscope for Crohn's strictures of the colon and ileo-colonic anastomosis has established efficacy and safety. In addition, EBD using balloon-assisted enteroscopy has recently been applied for small bowel Crohn's strictures. Although the evidence is not strong, EBD may become an alternative to surgery in small bowel strictures in CD. EBD and other new methods such as self-expanding stent implantation for Crohn's strictures may be useful and safe; however, it is important to address several issues regarding these interventions and to establish a protocol for combined therapies. |
| first_indexed | 2024-12-21T18:46:56Z |
| format | Article |
| id | doaj.art-256b86c3ca5d4fc2a1a9de05d3c87579 |
| institution | Directory Open Access Journal |
| issn | 1598-9100 |
| language | English |
| last_indexed | 2024-12-21T18:46:56Z |
| publishDate | 2017-04-01 |
| publisher | Korean Association for the Study of Intestinal Diseases |
| record_format | Article |
| series | Intestinal Research |
| spelling | doaj.art-256b86c3ca5d4fc2a1a9de05d3c875792022-12-21T18:53:52ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002017-04-0115216617310.5217/ir.2017.15.2.166ir.2017.15.2.166Current status of endoscopic balloon dilation for Crohn's diseaseFumihito Hirai0Inflammatory Bowel Disease Center, Fukuoka University Chikushi Hospital, Fukuoka, Japan.The therapeutic target in Crohn's disease (CD) has been raised to the achievement of mucosal healing. Although effective treatments that target cytokines and other molecules has been widely used for CD, intestinal strictures are still a major cause of surgery. Endoscopic balloon dilation (EBD) is known to be an effective and safe intervention for intestinal strictures in CD. Since frequent intestinal resection often results in short bowel syndrome and can decrease the quality of life, EBD can help avoid surgery. EBD with a conventional colonoscope for Crohn's strictures of the colon and ileo-colonic anastomosis has established efficacy and safety. In addition, EBD using balloon-assisted enteroscopy has recently been applied for small bowel Crohn's strictures. Although the evidence is not strong, EBD may become an alternative to surgery in small bowel strictures in CD. EBD and other new methods such as self-expanding stent implantation for Crohn's strictures may be useful and safe; however, it is important to address several issues regarding these interventions and to establish a protocol for combined therapies.https://doi.org/10.5217/ir.2017.15.2.166Endoscopic balloon dilationCrohn diseaseColorectal strictureIleo-colonic anastomotic strictureSmall bowel stricture |
| spellingShingle | Fumihito Hirai Current status of endoscopic balloon dilation for Crohn's disease Intestinal Research Endoscopic balloon dilation Crohn disease Colorectal stricture Ileo-colonic anastomotic stricture Small bowel stricture |
| title | Current status of endoscopic balloon dilation for Crohn's disease |
| title_full | Current status of endoscopic balloon dilation for Crohn's disease |
| title_fullStr | Current status of endoscopic balloon dilation for Crohn's disease |
| title_full_unstemmed | Current status of endoscopic balloon dilation for Crohn's disease |
| title_short | Current status of endoscopic balloon dilation for Crohn's disease |
| title_sort | current status of endoscopic balloon dilation for crohn s disease |
| topic | Endoscopic balloon dilation Crohn disease Colorectal stricture Ileo-colonic anastomotic stricture Small bowel stricture |
| url | https://doi.org/10.5217/ir.2017.15.2.166 |
| work_keys_str_mv | AT fumihitohirai currentstatusofendoscopicballoondilationforcrohnsdisease |