[PROVISIONAL] Perforin Gene PRF1 c.900C>T Polymorphism and HIV-1 Vertical Transmission

[PROVISIONAL] Perforin Gene PRF1 c.900C>T Polymorphism and HIV-1 Vertical Transmission

Abstract Perforin-1, component of the immune system, is able to control Human Immunodeficiency Virus-1 (HIV-1) replication and it could be involved in HIV-1 mother-to-child transmission (MTCT). This study aims at evaluating the role of c.900C>T PRF1 gene (encoding for perforin-1) polymorphism (rs...

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Bibliographic Details
Main Authors: Luisa Zupin, Vania Polesello, Anselmo Jiro Kamada, Rossella Gratton, Ludovica Segat, Louise Kuhn, Sergio Crovella
Format: Article
Language:English
Published: Sociedade Brasileira de Genética
Series:Genetics and Molecular Biology
Subjects:
PRF1
perforin
HIV-1 susceptibility
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019005019104&lng=en&tlng=en

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