Influence of choline chloride-based NADES on the composition of Myristica fragrans Houtt. essential oil
Natural deep eutectic solvents (NADES) have emerged as green extracting solvents in recent years. In this study, a variety of choline chloride (ChCl)-based natural deep eutectic solvents (NADES) were used as co-solvents for the hydrodistillation of nutmeg with the aim to obtain M. fragrans essential...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-05-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022008192 |
| _version_ | 1818209356342099968 |
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| author | Daniela Lanari Claudia Zadra Francesca Negro Rima Njem Maria Carla Marcotullio |
| author_facet | Daniela Lanari Claudia Zadra Francesca Negro Rima Njem Maria Carla Marcotullio |
| author_sort | Daniela Lanari |
| collection | DOAJ |
| description | Natural deep eutectic solvents (NADES) have emerged as green extracting solvents in recent years. In this study, a variety of choline chloride (ChCl)-based natural deep eutectic solvents (NADES) were used as co-solvents for the hydrodistillation of nutmeg with the aim to obtain M. fragrans essential oil (EO) in higher yield and with a lower content of toxic phenylpropenoids (e.g. myristicin and safrole). The influence of ChCl-based NADES as additives in the hydrodistillation process was studied. The results showed that NADES additives improved the yield of the extracted essential oil and influenced its composition leading to a decrease in toxic phenylpropenoids. Best results were achieved by using ChCl-CA NADES ultrasound-assisted pretreatment coupled with traditional 2 h Clevenger hydrodistillation that increased the yield of the EO from 0.98% (traditional) to 1.41% and a decrease of the phenylpropenoids amount in the essential oil. |
| first_indexed | 2024-12-12T04:59:24Z |
| format | Article |
| id | doaj.art-25733493c43d4f93a87ff44e338f112a |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-12-12T04:59:24Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-25733493c43d4f93a87ff44e338f112a2022-12-22T00:37:16ZengElsevierHeliyon2405-84402022-05-0185e09531Influence of choline chloride-based NADES on the composition of Myristica fragrans Houtt. essential oilDaniela Lanari0Claudia Zadra1Francesca Negro2Rima Njem3Maria Carla Marcotullio4Dipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Via Fabretti, 48-06123, Perugia, ItalyDipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Via Fabretti, 48-06123, Perugia, ItalyDipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Via Fabretti, 48-06123, Perugia, ItalyDipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Via Fabretti, 48-06123, Perugia, ItalyCorresponding author.; Dipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Via Fabretti, 48-06123, Perugia, ItalyNatural deep eutectic solvents (NADES) have emerged as green extracting solvents in recent years. In this study, a variety of choline chloride (ChCl)-based natural deep eutectic solvents (NADES) were used as co-solvents for the hydrodistillation of nutmeg with the aim to obtain M. fragrans essential oil (EO) in higher yield and with a lower content of toxic phenylpropenoids (e.g. myristicin and safrole). The influence of ChCl-based NADES as additives in the hydrodistillation process was studied. The results showed that NADES additives improved the yield of the extracted essential oil and influenced its composition leading to a decrease in toxic phenylpropenoids. Best results were achieved by using ChCl-CA NADES ultrasound-assisted pretreatment coupled with traditional 2 h Clevenger hydrodistillation that increased the yield of the EO from 0.98% (traditional) to 1.41% and a decrease of the phenylpropenoids amount in the essential oil.http://www.sciencedirect.com/science/article/pii/S2405844022008192Myristica fragransNutmegEssential oilNADESCholine chlorideUltrasound pretreatment |
| spellingShingle | Daniela Lanari Claudia Zadra Francesca Negro Rima Njem Maria Carla Marcotullio Influence of choline chloride-based NADES on the composition of Myristica fragrans Houtt. essential oil Heliyon Myristica fragrans Nutmeg Essential oil NADES Choline chloride Ultrasound pretreatment |
| title | Influence of choline chloride-based NADES on the composition of Myristica fragrans Houtt. essential oil |
| title_full | Influence of choline chloride-based NADES on the composition of Myristica fragrans Houtt. essential oil |
| title_fullStr | Influence of choline chloride-based NADES on the composition of Myristica fragrans Houtt. essential oil |
| title_full_unstemmed | Influence of choline chloride-based NADES on the composition of Myristica fragrans Houtt. essential oil |
| title_short | Influence of choline chloride-based NADES on the composition of Myristica fragrans Houtt. essential oil |
| title_sort | influence of choline chloride based nades on the composition of myristica fragrans houtt essential oil |
| topic | Myristica fragrans Nutmeg Essential oil NADES Choline chloride Ultrasound pretreatment |
| url | http://www.sciencedirect.com/science/article/pii/S2405844022008192 |
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