PFAPA syndrome in a 2-year-old girl: a case report and literature review
PFAPA syndrome is the most common periodic fever syndrome in our geographic zone. It usually develops in children under 5 years of age and is classified as an autoinflammatory disease. PFAPA syndrome is characterised by episodes of high fever (>39°C) accompanied by aphthous stomatitis, pharyngi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Medical Communications Sp. z o.o.
2018-03-01
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| Series: | Pediatria i Medycyna Rodzinna |
| Subjects: | |
| Online Access: | http://www.pimr.pl/index.php/issues/2018-vol-14-no-1/pfapa-syndrome-in-a-2-year-old-girl-a-case-report-and-literature-review?aid=1165 |
| _version_ | 1819154306297757696 |
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| author | Jakub Haracz Monika Tadla Grzegorz Fleszar Jacek Postępski |
| author_facet | Jakub Haracz Monika Tadla Grzegorz Fleszar Jacek Postępski |
| author_sort | Jakub Haracz |
| collection | DOAJ |
| description | PFAPA syndrome is the most common periodic fever syndrome in our geographic zone. It usually develops in children under
5 years of age and is classified as an autoinflammatory disease. PFAPA syndrome is characterised by episodes of high fever
(>39°C) accompanied by aphthous stomatitis, pharyngitis, and cervical lymphadenopathy, which occur cyclically at 25–35-day
intervals and last between 3 and 6 days. Patients experience no symptoms between these episodes. The disease resolves with
age. The cause of PFAPA and the predisposing factors remain unknown. The paper presents a clinical case of a 2-year-old
girl diagnosed in the Department of Paediatric Pulmonology and Rheumatology of the Medical University of Lublin due to
recurrent fever episodes. After exclusion of other causes, PFAPA syndrome was diagnosed. Corticosteroid treatment was
used and good therapeutic response was achieved. The paper also presents a literature review on the current diagnosis and
treatment modalities in PFAPA. |
| first_indexed | 2024-12-22T15:18:59Z |
| format | Article |
| id | doaj.art-2574177749ab407f91efc8a02b089877 |
| institution | Directory Open Access Journal |
| issn | 1734-1531 2451-0742 |
| language | English |
| last_indexed | 2024-12-22T15:18:59Z |
| publishDate | 2018-03-01 |
| publisher | Medical Communications Sp. z o.o. |
| record_format | Article |
| series | Pediatria i Medycyna Rodzinna |
| spelling | doaj.art-2574177749ab407f91efc8a02b0898772022-12-21T18:21:40ZengMedical Communications Sp. z o.o.Pediatria i Medycyna Rodzinna1734-15312451-07422018-03-01141889510.15557/PiMR.2018.0009PFAPA syndrome in a 2-year-old girl: a case report and literature reviewJakub Haracz0Monika Tadla1Grzegorz Fleszar2Jacek Postępski3Student’s Paediatric Scientific Association at the Department of Pulmonology and Rheumatology, Medical University of Lublin, Lublin, PolandStudent’s Paediatric Scientific Association at the Department of Pulmonology and Rheumatology, Medical University of Lublin, Lublin, PolandStudent’s Paediatric Scientific Association at the Department of Pulmonology and Rheumatology, Medical University of Lublin, Lublin, PolandDepartment of Paediatric Pulmonology and Rheumatology, Medical University of Lublin, Lublin, PolandPFAPA syndrome is the most common periodic fever syndrome in our geographic zone. It usually develops in children under 5 years of age and is classified as an autoinflammatory disease. PFAPA syndrome is characterised by episodes of high fever (>39°C) accompanied by aphthous stomatitis, pharyngitis, and cervical lymphadenopathy, which occur cyclically at 25–35-day intervals and last between 3 and 6 days. Patients experience no symptoms between these episodes. The disease resolves with age. The cause of PFAPA and the predisposing factors remain unknown. The paper presents a clinical case of a 2-year-old girl diagnosed in the Department of Paediatric Pulmonology and Rheumatology of the Medical University of Lublin due to recurrent fever episodes. After exclusion of other causes, PFAPA syndrome was diagnosed. Corticosteroid treatment was used and good therapeutic response was achieved. The paper also presents a literature review on the current diagnosis and treatment modalities in PFAPA.http://www.pimr.pl/index.php/issues/2018-vol-14-no-1/pfapa-syndrome-in-a-2-year-old-girl-a-case-report-and-literature-review?aid=1165paediatricsfeverpharyngitiscervical adenitisaphthous stomatitis |
| spellingShingle | Jakub Haracz Monika Tadla Grzegorz Fleszar Jacek Postępski PFAPA syndrome in a 2-year-old girl: a case report and literature review Pediatria i Medycyna Rodzinna paediatrics fever pharyngitis cervical adenitis aphthous stomatitis |
| title | PFAPA syndrome in a 2-year-old girl: a case report and literature review |
| title_full | PFAPA syndrome in a 2-year-old girl: a case report and literature review |
| title_fullStr | PFAPA syndrome in a 2-year-old girl: a case report and literature review |
| title_full_unstemmed | PFAPA syndrome in a 2-year-old girl: a case report and literature review |
| title_short | PFAPA syndrome in a 2-year-old girl: a case report and literature review |
| title_sort | pfapa syndrome in a 2 year old girl a case report and literature review |
| topic | paediatrics fever pharyngitis cervical adenitis aphthous stomatitis |
| url | http://www.pimr.pl/index.php/issues/2018-vol-14-no-1/pfapa-syndrome-in-a-2-year-old-girl-a-case-report-and-literature-review?aid=1165 |
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