Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen
An elderly man was found to have a large right atrioventricular mass and pericardial effusion. He was diagnosed and treated as having primary cardiac lymphoma. A dose-attenuated chemotherapy regimen of rituximab, cyclophosphamide, vincristine, and prednisolone, with a cytoreductive pre-phase, afford...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-10-01
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| Series: | JACC: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666084919302529 |
| _version_ | 1818441481084469248 |
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| author | Amit K.J. Mandal, MBBS Faye L. Selby, MBBS Stuart Deoraj, MBBS Sofia Metaxa, MD Constantinos G. Missouris, MD |
| author_facet | Amit K.J. Mandal, MBBS Faye L. Selby, MBBS Stuart Deoraj, MBBS Sofia Metaxa, MD Constantinos G. Missouris, MD |
| author_sort | Amit K.J. Mandal, MBBS |
| collection | DOAJ |
| description | An elderly man was found to have a large right atrioventricular mass and pericardial effusion. He was diagnosed and treated as having primary cardiac lymphoma. A dose-attenuated chemotherapy regimen of rituximab, cyclophosphamide, vincristine, and prednisolone, with a cytoreductive pre-phase, afforded complete regression of disease with resolution of the patient’s symptoms, and without deterioration in cardiac function or immunosuppression. The patient remains well 12 months after presentation. (Level of Difficulty: Advanced.) |
| first_indexed | 2024-12-14T18:28:56Z |
| format | Article |
| id | doaj.art-25762d388cd64fc98b0e15dfd900be97 |
| institution | Directory Open Access Journal |
| issn | 2666-0849 |
| language | English |
| last_indexed | 2024-12-14T18:28:56Z |
| publishDate | 2019-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JACC: Case Reports |
| spelling | doaj.art-25762d388cd64fc98b0e15dfd900be972022-12-21T22:51:50ZengElsevierJACC: Case Reports2666-08492019-10-0113332336Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic RegimenAmit K.J. Mandal, MBBS0Faye L. Selby, MBBS1Stuart Deoraj, MBBS2Sofia Metaxa, MD3Constantinos G. Missouris, MD4Departments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, Berkshire, United KingdomDepartments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, Berkshire, United KingdomDepartments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, Berkshire, United KingdomDepartments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, Berkshire, United KingdomDepartments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, Berkshire, United Kingdom; Department of Cardiology, University of Cyprus Medical School, Nicosia, Cyprus; Address for correspondence: Prof. Constantinos G. Missouris, Departments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, Berkshire SL2 4HL, United Kingdom.An elderly man was found to have a large right atrioventricular mass and pericardial effusion. He was diagnosed and treated as having primary cardiac lymphoma. A dose-attenuated chemotherapy regimen of rituximab, cyclophosphamide, vincristine, and prednisolone, with a cytoreductive pre-phase, afforded complete regression of disease with resolution of the patient’s symptoms, and without deterioration in cardiac function or immunosuppression. The patient remains well 12 months after presentation. (Level of Difficulty: Advanced.)http://www.sciencedirect.com/science/article/pii/S2666084919302529cancercardiomyopathyright ventricletamponadetricuspid valve |
| spellingShingle | Amit K.J. Mandal, MBBS Faye L. Selby, MBBS Stuart Deoraj, MBBS Sofia Metaxa, MD Constantinos G. Missouris, MD Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen JACC: Case Reports cancer cardiomyopathy right ventricle tamponade tricuspid valve |
| title | Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen |
| title_full | Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen |
| title_fullStr | Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen |
| title_full_unstemmed | Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen |
| title_short | Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen |
| title_sort | complete regression of primary cardiac lymphoma with dose attenuated r cvp chemotherapeutic regimen |
| topic | cancer cardiomyopathy right ventricle tamponade tricuspid valve |
| url | http://www.sciencedirect.com/science/article/pii/S2666084919302529 |
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