Mesothelin promotes brain metastasis of non-small cell lung cancer by activating MET

Mesothelin promotes brain metastasis of non-small cell lung cancer by activating MET

Abstract Background Brain metastasis (BM) is common among cases of advanced non-small cell lung cancer (NSCLC) and is the leading cause of death for these patients. Mesothelin (MSLN), a tumor-associated antigen expressed in many solid tumors, has been reported to be involved in the progression of mu...

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Bibliographic Details
Main Authors: Shengkai Xia, Wenzhe Duan, Mingxin Xu, Mengqi Li, Mengyi Tang, Song Wei, Manqing Lin, Encheng Li, Wenwen Liu, Qi Wang
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
MSLN
NSCLC
Brain metastasis (BM)
Blood-brain barrier (BBB)
MET
Online Access:https://doi.org/10.1186/s13046-024-03015-w

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