Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise

Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise

Skeletal muscle atrophy is a critical component of the ageing process. Age-related muscle wasting is due to disrupted muscle protein turnover, a process mediated in part by the ubiquitin proteasome pathway (UPP). Additionally, older subjects have been observed to have an attenuated anabolic response...

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Bibliographic Details
Main Authors: Renae Jane Stefanetti, Evelyn eZacharewicz, Paul eDella Gatta, Andrew eGarnham, Aaron Paul Russell, Severine eLamon
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Physiology
Subjects:
Sarcopenia
skeletal muscle
ubiquitin-proteasome system
Resistance exercise
muscle protein breakdown
atrogene signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00030/full

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