Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic stroke
Aims: The aim of this study was to asses the platelet activation in the acute phase of ischemic stroke and transient ischemic attack (TIA) by defining p-selectin (CD62) expression by flow cytometry in vivo – without stimulation with agonists. We also studied whether antiplatelet therapy supresses th...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2018-06-01
|
| Series: | Acta Medica Martiniana |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/acm-2018-0002 |
| _version_ | 1819276122124189696 |
|---|---|
| author | Kalmarova K Kurca E Nosal V Dluha J Ballova J Sokol J Skornova I Stasko J Zolkova J Vadelova L |
| author_facet | Kalmarova K Kurca E Nosal V Dluha J Ballova J Sokol J Skornova I Stasko J Zolkova J Vadelova L |
| author_sort | Kalmarova K |
| collection | DOAJ |
| description | Aims: The aim of this study was to asses the platelet activation in the acute phase of ischemic stroke and transient ischemic attack (TIA) by defining p-selectin (CD62) expression by flow cytometry in vivo – without stimulation with agonists. We also studied whether antiplatelet therapy supresses the levels of baseline p-selectin expression and verified if there is a correlation between platelet CD62 expression and the type of ischemic stroke. |
| first_indexed | 2024-12-23T23:35:12Z |
| format | Article |
| id | doaj.art-257b62443ad74134a693d66b54aa3757 |
| institution | Directory Open Access Journal |
| issn | 1335-8421 |
| language | English |
| last_indexed | 2024-12-23T23:35:12Z |
| publishDate | 2018-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Medica Martiniana |
| spelling | doaj.art-257b62443ad74134a693d66b54aa37572022-12-21T17:25:52ZengSciendoActa Medica Martiniana1335-84212018-06-01181142010.2478/acm-2018-0002acm-2018-0002Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic strokeKalmarova K0Kurca E1Nosal V2Dluha J3Ballova J4Sokol J5Skornova I6Stasko J7Zolkova J8Vadelova L9Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicClinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicClinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicClinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicClinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicNational Center of Hemostasis and Thrombosis, Department of Hematology and Transfusiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicNational Center of Hemostasis and Thrombosis, Department of Hematology and Transfusiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicNational Center of Hemostasis and Thrombosis, Department of Hematology and Transfusiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicNational Center of Hemostasis and Thrombosis, Department of Hematology and Transfusiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicNational Center of Hemostasis and Thrombosis, Department of Hematology and Transfusiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak RepublicAims: The aim of this study was to asses the platelet activation in the acute phase of ischemic stroke and transient ischemic attack (TIA) by defining p-selectin (CD62) expression by flow cytometry in vivo – without stimulation with agonists. We also studied whether antiplatelet therapy supresses the levels of baseline p-selectin expression and verified if there is a correlation between platelet CD62 expression and the type of ischemic stroke.https://doi.org/10.2478/acm-2018-0002flow cytometryactivated plateletsischemic strokep-selectin |
| spellingShingle | Kalmarova K Kurca E Nosal V Dluha J Ballova J Sokol J Skornova I Stasko J Zolkova J Vadelova L Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic stroke Acta Medica Martiniana flow cytometry activated platelets ischemic stroke p-selectin |
| title | Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic stroke |
| title_full | Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic stroke |
| title_fullStr | Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic stroke |
| title_full_unstemmed | Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic stroke |
| title_short | Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic stroke |
| title_sort | measurement of platelet p selectin expression by flow cytometry in patients with acute ischemic stroke |
| topic | flow cytometry activated platelets ischemic stroke p-selectin |
| url | https://doi.org/10.2478/acm-2018-0002 |
| work_keys_str_mv | AT kalmarovak measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT kurcae measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT nosalv measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT dluhaj measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT ballovaj measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT sokolj measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT skornovai measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT staskoj measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT zolkovaj measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke AT vadeloval measurementofplateletpselectinexpressionbyflowcytometryinpatientswithacuteischemicstroke |