Regulatory T Cells and Pro-inflammatory Responses Predominate in Children with Tuberculosis

Regulatory T Cells and Pro-inflammatory Responses Predominate in Children with Tuberculosis

BackgroundFollowing infection with Mycobacterium tuberculosis (M.tb), children are more susceptible to develop disease particularly extrapulmonary disease than adults. The exact mechanisms required for containment of M.tb are not known, but would be important to identify correlates of protection.Obj...

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Bibliographic Details
Main Authors: Elizabeth Whittaker, Mark Nicol, Heather J. Zar, Beate Kampmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
extrapulmonary
pediatric
mycobacterial immunity
regulatory T cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00448/full

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