Neuroprotective Effects of a New Derivative of Chlojaponilactone B against Oxidative Damaged Induced by Hydrogen Peroxide in PC12 Cells

Neuroprotective Effects of a New Derivative of Chlojaponilactone B against Oxidative Damaged Induced by Hydrogen Peroxide in PC12 Cells

A new sesquiterpenoid (<b>1</b>) was obtained by hydrogenating Chlojaponilactone B. The structure of <b>1</b> was elucidated according to a combination of NMR, HRESIMS, and NOE diffraction data. The treatment of H<sub>2</sub>O<sub>2</sub> in a PC12 cel...

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Bibliographic Details
Main Authors: Shaoxia Ye, Qiyin Wen, Longping Zhu, Chunguo Qian, Depo Yang, Zhimin Zhao
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
sesquiterpene
neuroprotection
PC12 cells
ROS
Nrf2
Online Access:https://www.mdpi.com/1420-3049/27/18/6049

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