Transcription factors organize into functional groups on the linear genome and in 3D chromatin

Transcription factors organize into functional groups on the linear genome and in 3D chromatin

Transcription factors (TFs) and their binding sites have evolved to interact cooperatively or competitively with each other. Here we examine in detail, across multiple cell lines, such cooperation or competition among TFs both in sequential and spatial proximity (using chromatin conformation capture...

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Bibliographic Details
Main Authors: Rakesh Netha Vadnala, Sridhar Hannenhalli, Leelavati Narlikar, Rahul Siddharthan
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
Chromatin
Transcription factors
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023054191

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