Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature
Abstract Background Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life (mostly if multifocal) and there is a lack of standardized recommendations for the pediatric age. Case presentation We describe the case of a 9-year-old boy with a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-05-01
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| Series: | BMC Urology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12894-019-0469-1 |
| _version_ | 1818150709959327744 |
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| author | Palma Maurizi Michele Antonio Capozza Silvia Triarico Maria Luisa Perrotta Vito Briganti Antonio Ruggiero |
| author_facet | Palma Maurizi Michele Antonio Capozza Silvia Triarico Maria Luisa Perrotta Vito Briganti Antonio Ruggiero |
| author_sort | Palma Maurizi |
| collection | DOAJ |
| description | Abstract Background Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life (mostly if multifocal) and there is a lack of standardized recommendations for the pediatric age. Case presentation We describe the case of a 9-year-old boy with a diagnosis of PUNLMP, who underwent to cystoscopic lesion removal and later to endoscopic lesion removal and intra-bladder Mitomycin-c (MMC) instillations for relapsed disease. Follow-up investigations at five years showed disease negativity. Conclusions Intra-bladder MMC instillation may allow obtaining the complete remission with bladder-sparing for paediatric patients with a high-risk relapsed PUNLMP. |
| first_indexed | 2024-12-11T13:27:15Z |
| format | Article |
| id | doaj.art-2584dfdeeba5475c8ef6b1b75e9509eb |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-12-11T13:27:15Z |
| publishDate | 2019-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-2584dfdeeba5475c8ef6b1b75e9509eb2022-12-22T01:05:29ZengBMCBMC Urology1471-24902019-05-011911310.1186/s12894-019-0469-1Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literaturePalma Maurizi0Michele Antonio Capozza1Silvia Triarico2Maria Luisa Perrotta3Vito Briganti4Antonio Ruggiero5Pediatric Oncology Unit, Foundation “A. Gemelli” Hospital IRCCS - Catholic University of Sacred HearthPediatric Oncology Unit, Foundation “A. Gemelli” Hospital IRCCS - Catholic University of Sacred HearthPediatric Oncology Unit, Foundation “A. Gemelli” Hospital IRCCS - Catholic University of Sacred HearthPediatric Surgery Unit, San Camillo Forlanini HospitalPediatric Surgery Unit, San Camillo Forlanini HospitalPediatric Oncology Unit, Foundation “A. Gemelli” Hospital IRCCS - Catholic University of Sacred HearthAbstract Background Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life (mostly if multifocal) and there is a lack of standardized recommendations for the pediatric age. Case presentation We describe the case of a 9-year-old boy with a diagnosis of PUNLMP, who underwent to cystoscopic lesion removal and later to endoscopic lesion removal and intra-bladder Mitomycin-c (MMC) instillations for relapsed disease. Follow-up investigations at five years showed disease negativity. Conclusions Intra-bladder MMC instillation may allow obtaining the complete remission with bladder-sparing for paediatric patients with a high-risk relapsed PUNLMP.http://link.springer.com/article/10.1186/s12894-019-0469-1Papillary urothelial bladder neoplasmLow grade of malignancyRelapsed diseaseIntrabbladder chemotherapy |
| spellingShingle | Palma Maurizi Michele Antonio Capozza Silvia Triarico Maria Luisa Perrotta Vito Briganti Antonio Ruggiero Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature BMC Urology Papillary urothelial bladder neoplasm Low grade of malignancy Relapsed disease Intrabbladder chemotherapy |
| title | Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature |
| title_full | Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature |
| title_fullStr | Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature |
| title_full_unstemmed | Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature |
| title_short | Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature |
| title_sort | relapsed papillary urothelial neoplasm of low malignant potential punlmp of the young age a case report and a review of the literature |
| topic | Papillary urothelial bladder neoplasm Low grade of malignancy Relapsed disease Intrabbladder chemotherapy |
| url | http://link.springer.com/article/10.1186/s12894-019-0469-1 |
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