Renal artery revascularization is a controversial treatment strategy for renal artery stenosis: A case series and a brief review of the current literature

Renal artery stenosis (RAS) may cause secondary hypertension, progressive decline in renal function, and cardiac destabilization syndromes including “flash” pulmonary edema, recurrent congestive heart failure, and cerebro-cardiovascular disease. Atherosclerotic lesions, fibromuscular dysplasia, and...

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Main Authors: Georgios Triantis, Georgios K. Chalikias, Emmanouil Ioannidis, Anna Dagre, Dimitrios N. Tziakas
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Hellenic Journal of Cardiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1109966622000343
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author Georgios Triantis
Georgios K. Chalikias
Emmanouil Ioannidis
Anna Dagre
Dimitrios N. Tziakas
author_facet Georgios Triantis
Georgios K. Chalikias
Emmanouil Ioannidis
Anna Dagre
Dimitrios N. Tziakas
author_sort Georgios Triantis
collection DOAJ
description Renal artery stenosis (RAS) may cause secondary hypertension, progressive decline in renal function, and cardiac destabilization syndromes including “flash” pulmonary edema, recurrent congestive heart failure, and cerebro-cardiovascular disease. Atherosclerotic lesions, fibromuscular dysplasia, and vasculitides are the pathophysiological basis of the disease. Common therapeutic pathways for RAS include medical therapy and revascularization with or without stenting. Randomized controlled trials evaluating renal revascularization have not reported any advantages of revascularization over medical therapy alone in terms of renal function improvement or prevention of cardiovascular events. However, mounting clinical experience suggests that the best strategy in RAS management is to identify which patients are most likely to benefit from renal artery stenting and to optimize the safety and durability of the procedure. This review presents 3 cases of patients who have undergone renal revascularization and discusses the available clinical evidence for the identification of RAS patients who will potentially respond well to revascularization.
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spelling doaj.art-2589e6bdcc4d420d97c10c5b84d893052022-12-22T00:26:38ZengElsevierHellenic Journal of Cardiology1109-96662022-05-01654248Renal artery revascularization is a controversial treatment strategy for renal artery stenosis: A case series and a brief review of the current literatureGeorgios Triantis0Georgios K. Chalikias1Emmanouil Ioannidis2Anna Dagre3Dimitrios N. Tziakas4Department of Cardiology, Sismanoglion Hospital, Athens, GreeceDepartment of Cardiology, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceDepartment of Cardiology, Sismanoglion Hospital, Athens, GreeceDepartment of Cardiology, Thriassio General Hospital, Athens, GreeceDepartment of Cardiology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece; Corresponding author. Dimitrios N. Tziakas, Cardiology Department, Medical School, Democritus University of Thrace, Dragana, 68100, Alexandroupolis, Greece. Tel.: +30 25513 53205, fax: +30 25513 53245.Renal artery stenosis (RAS) may cause secondary hypertension, progressive decline in renal function, and cardiac destabilization syndromes including “flash” pulmonary edema, recurrent congestive heart failure, and cerebro-cardiovascular disease. Atherosclerotic lesions, fibromuscular dysplasia, and vasculitides are the pathophysiological basis of the disease. Common therapeutic pathways for RAS include medical therapy and revascularization with or without stenting. Randomized controlled trials evaluating renal revascularization have not reported any advantages of revascularization over medical therapy alone in terms of renal function improvement or prevention of cardiovascular events. However, mounting clinical experience suggests that the best strategy in RAS management is to identify which patients are most likely to benefit from renal artery stenting and to optimize the safety and durability of the procedure. This review presents 3 cases of patients who have undergone renal revascularization and discusses the available clinical evidence for the identification of RAS patients who will potentially respond well to revascularization.http://www.sciencedirect.com/science/article/pii/S1109966622000343renal artery stenosisrenal revascularizationmedical therapyrenal artery stenting
spellingShingle Georgios Triantis
Georgios K. Chalikias
Emmanouil Ioannidis
Anna Dagre
Dimitrios N. Tziakas
Renal artery revascularization is a controversial treatment strategy for renal artery stenosis: A case series and a brief review of the current literature
Hellenic Journal of Cardiology
renal artery stenosis
renal revascularization
medical therapy
renal artery stenting
title Renal artery revascularization is a controversial treatment strategy for renal artery stenosis: A case series and a brief review of the current literature
title_full Renal artery revascularization is a controversial treatment strategy for renal artery stenosis: A case series and a brief review of the current literature
title_fullStr Renal artery revascularization is a controversial treatment strategy for renal artery stenosis: A case series and a brief review of the current literature
title_full_unstemmed Renal artery revascularization is a controversial treatment strategy for renal artery stenosis: A case series and a brief review of the current literature
title_short Renal artery revascularization is a controversial treatment strategy for renal artery stenosis: A case series and a brief review of the current literature
title_sort renal artery revascularization is a controversial treatment strategy for renal artery stenosis a case series and a brief review of the current literature
topic renal artery stenosis
renal revascularization
medical therapy
renal artery stenting
url http://www.sciencedirect.com/science/article/pii/S1109966622000343
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