The association of genetic factors with serum calretinin levels in asbestos-related diseases
Asbestos exposure is associated with different asbestos-related diseases, including malignant mesothelioma (MM). MM diagnosis is confirmed with immunohistochemical analysis of several markers, including calretinin. Increased circulating calretinin was also observed in MM. The aim of the study was to...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
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Sciendo
2023-11-01
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Series: | Radiology and Oncology |
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Online Access: | https://doi.org/10.2478/raon-2023-0061 |
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author | Zupanc Cita Franko Alenka Strbac Danijela Kovac Viljem Dolzan Vita Goricar Katja |
author_facet | Zupanc Cita Franko Alenka Strbac Danijela Kovac Viljem Dolzan Vita Goricar Katja |
author_sort | Zupanc Cita |
collection | DOAJ |
description | Asbestos exposure is associated with different asbestos-related diseases, including malignant mesothelioma (MM). MM diagnosis is confirmed with immunohistochemical analysis of several markers, including calretinin. Increased circulating calretinin was also observed in MM. The aim of the study was to determine if CALB2 polymorphisms or polymorphisms in genes that can regulate calretinin expression are associated with serum calretinin levels or MM susceptibility. |
first_indexed | 2024-03-08T22:20:59Z |
format | Article |
id | doaj.art-258a09d42aba4cfbb6e93417240c7d91 |
institution | Directory Open Access Journal |
issn | 1581-3207 |
language | English |
last_indexed | 2024-03-08T22:20:59Z |
publishDate | 2023-11-01 |
publisher | Sciendo |
record_format | Article |
series | Radiology and Oncology |
spelling | doaj.art-258a09d42aba4cfbb6e93417240c7d912023-12-18T12:45:42ZengSciendoRadiology and Oncology1581-32072023-11-0157447348610.2478/raon-2023-0061The association of genetic factors with serum calretinin levels in asbestos-related diseasesZupanc Cita0Franko Alenka1Strbac Danijela2Kovac Viljem3Dolzan Vita4Goricar Katja5Military Medical Unit-Slovenian Army, Ljubljana, SloveniaUniversity of Ljubljana, Faculty of Medicine, Ljubljana, SloveniaUniversity of Ljubljana, Faculty of Medicine, Ljubljana, SloveniaUniversity of Ljubljana, Faculty of Medicine, Ljubljana, SloveniaUniversity of Ljubljana, Faculty of Medicine, Institute of Biochemistry and Molecular Genetics, Pharmacogenetics Laboratory, Ljubljana, SloveniaUniversity of Ljubljana, Faculty of Medicine, Institute of Biochemistry and Molecular Genetics, Pharmacogenetics Laboratory, Ljubljana, SloveniaAsbestos exposure is associated with different asbestos-related diseases, including malignant mesothelioma (MM). MM diagnosis is confirmed with immunohistochemical analysis of several markers, including calretinin. Increased circulating calretinin was also observed in MM. The aim of the study was to determine if CALB2 polymorphisms or polymorphisms in genes that can regulate calretinin expression are associated with serum calretinin levels or MM susceptibility.https://doi.org/10.2478/raon-2023-0061malignant mesotheliomacalretinincalb2asbestos-related diseasepolymorphism |
spellingShingle | Zupanc Cita Franko Alenka Strbac Danijela Kovac Viljem Dolzan Vita Goricar Katja The association of genetic factors with serum calretinin levels in asbestos-related diseases Radiology and Oncology malignant mesothelioma calretinin calb2 asbestos-related disease polymorphism |
title | The association of genetic factors with serum calretinin levels in asbestos-related diseases |
title_full | The association of genetic factors with serum calretinin levels in asbestos-related diseases |
title_fullStr | The association of genetic factors with serum calretinin levels in asbestos-related diseases |
title_full_unstemmed | The association of genetic factors with serum calretinin levels in asbestos-related diseases |
title_short | The association of genetic factors with serum calretinin levels in asbestos-related diseases |
title_sort | association of genetic factors with serum calretinin levels in asbestos related diseases |
topic | malignant mesothelioma calretinin calb2 asbestos-related disease polymorphism |
url | https://doi.org/10.2478/raon-2023-0061 |
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