The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy
Clozapine, a commonly used atypical antipsychotic, can precipitate a severe withdrawal syndrome. In this report, we describe a case of delirium with catatonic features emerging after the immediate cessation of clozapine subsequent to concerns of developing neuroleptic malignant syndrome. After multi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2017-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2017/1783545 |
| _version_ | 1798045626738409472 |
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| author | Anish Modak Arne Åhlin |
| author_facet | Anish Modak Arne Åhlin |
| author_sort | Anish Modak |
| collection | DOAJ |
| description | Clozapine, a commonly used atypical antipsychotic, can precipitate a severe withdrawal syndrome. In this report, we describe a case of delirium with catatonic features emerging after the immediate cessation of clozapine subsequent to concerns of developing neuroleptic malignant syndrome. After multiple treatments were found to be inefficacious, electroconvulsive therapy (ECT) was initiated, resulting in significant improvement. A literature search revealed six previous cases of clozapine-withdrawal syndromes of varied symptomatology treated with ECT. To our knowledge, the present case represents the first reported clozapine-withdrawal delirium treated successfully with ECT. |
| first_indexed | 2024-04-11T23:25:18Z |
| format | Article |
| id | doaj.art-258d5bd6d1594c54b151c710103b57bb |
| institution | Directory Open Access Journal |
| issn | 2090-682X 2090-6838 |
| language | English |
| last_indexed | 2024-04-11T23:25:18Z |
| publishDate | 2017-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj.art-258d5bd6d1594c54b151c710103b57bb2022-12-22T03:57:21ZengHindawi LimitedCase Reports in Psychiatry2090-682X2090-68382017-01-01201710.1155/2017/17835451783545The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive TherapyAnish Modak0Arne Åhlin1Adult Mental Health Unit, The Canberra Hospital, ACT Health, GPO Box 825, Canberra, ACT 2601, AustraliaAdult Mental Health Unit, The Canberra Hospital, ACT Health, GPO Box 825, Canberra, ACT 2601, AustraliaClozapine, a commonly used atypical antipsychotic, can precipitate a severe withdrawal syndrome. In this report, we describe a case of delirium with catatonic features emerging after the immediate cessation of clozapine subsequent to concerns of developing neuroleptic malignant syndrome. After multiple treatments were found to be inefficacious, electroconvulsive therapy (ECT) was initiated, resulting in significant improvement. A literature search revealed six previous cases of clozapine-withdrawal syndromes of varied symptomatology treated with ECT. To our knowledge, the present case represents the first reported clozapine-withdrawal delirium treated successfully with ECT.http://dx.doi.org/10.1155/2017/1783545 |
| spellingShingle | Anish Modak Arne Åhlin The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy Case Reports in Psychiatry |
| title | The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy |
| title_full | The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy |
| title_fullStr | The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy |
| title_full_unstemmed | The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy |
| title_short | The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy |
| title_sort | treatment of clozapine withdrawal delirium with electroconvulsive therapy |
| url | http://dx.doi.org/10.1155/2017/1783545 |
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