Hydroxytyrosol Inhibits MDSCs and Promotes M1 Macrophages in Mice With Orthotopic Pancreatic Tumor

Hydroxytyrosol Inhibits MDSCs and Promotes M1 Macrophages in Mice With Orthotopic Pancreatic Tumor

The poor immunotherapy of pancreatic cancer is mainly due to its complex immunosuppressive microenvironment. The Mediterranean diet contributes to low cancer incidence. Hydroxytyrosol (HT) derived from olive oil has multiple health-promoting effects, but its therapeutic effect on pancreatic cancer r...

Full description

Bibliographic Details
Main Authors: Botao Wang, Lei Yang, Tianyu Liu, Jing Xun, Yuzhen Zhuo, Lanqiu Zhang, Qi Zhang, Ximo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
hydroxytyrosol
pancreatic cancer
MDSCs
M1 macrophages
stat3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.759172/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.759172/full

Similar Items