Clinical profile of patients with anterior nodular scleritis in India

Purpose: To report the clinical profile of a series of anterior nodular scleritis in Indian population. Methods: We conducted a retrospective review of medical records of 140 eyes of 123 consecutive patients with nodular scleritis who presented to a tertiary eye care institute between 2007 and 2018....

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Main Authors: Gazal Patnaik, Sridharan Sudharshan, Amala E George, Sudha K Ganesh, Jyotirmay Biswas, Parthopratim Dutta Majumder
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=1925;epage=1928;aulast=Patnaik
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author Gazal Patnaik
Sridharan Sudharshan
Amala E George
Sudha K Ganesh
Jyotirmay Biswas
Parthopratim Dutta Majumder
author_facet Gazal Patnaik
Sridharan Sudharshan
Amala E George
Sudha K Ganesh
Jyotirmay Biswas
Parthopratim Dutta Majumder
author_sort Gazal Patnaik
collection DOAJ
description Purpose: To report the clinical profile of a series of anterior nodular scleritis in Indian population. Methods: We conducted a retrospective review of medical records of 140 eyes of 123 consecutive patients with nodular scleritis who presented to a tertiary eye care institute between 2007 and 2018. Results: The mean age at presentation was 46.8 ± 13.1 years and 70.7% of the patients were female. Bilateral involvement was observed in 14% patients. The most common presenting symptom was redness (92.6%) and ocular pain (69.1%). Twenty-seven patients (22%) had some systemic association and rheumatoid arthritis (5%) was the most common autoimmune disease. Presumed ocular tuberculosis was diagnosed in 13% patients. Methotrexate was the most common immunosuppressive used in these patients and an additional immunosuppressive was required in 6.5% patients. Recurrence of inflammation was observed in 74.8% patients. Deterioration of vision noted in 2.8% eyes. Conclusion: Tuberculosis remains an important cause of nodular scleritis in India. Recurrence of scleritis is common in nodular scleritis and cases with non infectious nodular scleritis often require treatment with immune suppressives.
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spelling doaj.art-2593a5d9b84c4a45bc91bc713d3a79852022-12-22T01:25:36ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-016891925192810.4103/ijo.IJO_2154_19Clinical profile of patients with anterior nodular scleritis in IndiaGazal PatnaikSridharan SudharshanAmala E GeorgeSudha K GaneshJyotirmay BiswasParthopratim Dutta MajumderPurpose: To report the clinical profile of a series of anterior nodular scleritis in Indian population. Methods: We conducted a retrospective review of medical records of 140 eyes of 123 consecutive patients with nodular scleritis who presented to a tertiary eye care institute between 2007 and 2018. Results: The mean age at presentation was 46.8 ± 13.1 years and 70.7% of the patients were female. Bilateral involvement was observed in 14% patients. The most common presenting symptom was redness (92.6%) and ocular pain (69.1%). Twenty-seven patients (22%) had some systemic association and rheumatoid arthritis (5%) was the most common autoimmune disease. Presumed ocular tuberculosis was diagnosed in 13% patients. Methotrexate was the most common immunosuppressive used in these patients and an additional immunosuppressive was required in 6.5% patients. Recurrence of inflammation was observed in 74.8% patients. Deterioration of vision noted in 2.8% eyes. Conclusion: Tuberculosis remains an important cause of nodular scleritis in India. Recurrence of scleritis is common in nodular scleritis and cases with non infectious nodular scleritis often require treatment with immune suppressives.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=1925;epage=1928;aulast=Patnaikanterior nodular scleritiscyclophosphamidemethotrexatescleritistuberculosis
spellingShingle Gazal Patnaik
Sridharan Sudharshan
Amala E George
Sudha K Ganesh
Jyotirmay Biswas
Parthopratim Dutta Majumder
Clinical profile of patients with anterior nodular scleritis in India
Indian Journal of Ophthalmology
anterior nodular scleritis
cyclophosphamide
methotrexate
scleritis
tuberculosis
title Clinical profile of patients with anterior nodular scleritis in India
title_full Clinical profile of patients with anterior nodular scleritis in India
title_fullStr Clinical profile of patients with anterior nodular scleritis in India
title_full_unstemmed Clinical profile of patients with anterior nodular scleritis in India
title_short Clinical profile of patients with anterior nodular scleritis in India
title_sort clinical profile of patients with anterior nodular scleritis in india
topic anterior nodular scleritis
cyclophosphamide
methotrexate
scleritis
tuberculosis
url http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=1925;epage=1928;aulast=Patnaik
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