A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case report
Lymphoplasmacyte-rich meningioma (LPRM) is a rare subtype of meningioma, the specific pathogenesis of which remains unclear. Herein, we report the case of a 48-year-old Asian man who experienced progressive deafness and limb weakness. Magnetic resonance imaging revealed extramedullary masses diffuse...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2022-12-01
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| Series: | Translational Neuroscience |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tnsci-2022-0263 |
| _version_ | 1797947589988974592 |
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| author | Zhu Siyao Zou Yuting Wang Ya Xie Gongxun Xiao Shengying Zeng Furen Lu Yichen |
| author_facet | Zhu Siyao Zou Yuting Wang Ya Xie Gongxun Xiao Shengying Zeng Furen Lu Yichen |
| author_sort | Zhu Siyao |
| collection | DOAJ |
| description | Lymphoplasmacyte-rich meningioma (LPRM) is a rare subtype of meningioma, the specific pathogenesis of which remains unclear. Herein, we report the case of a 48-year-old Asian man who experienced progressive deafness and limb weakness. Magnetic resonance imaging revealed extramedullary masses diffusely growing, wrapping, and compressing the cervical spinal cord. The dural lesion was partially excised by surgery, and postoperative pathological examination confirmed the diagnosis of LPRM. Diffuse LPRM is extremely rare, and its treatment is challenging owing to difficulties associated with surgery and the uncertain efficacy of traditional therapies. Therefore, further clinical practice and basic research are needed to improve the prognosis of diffuse LPRM. |
| first_indexed | 2024-04-10T21:30:18Z |
| format | Article |
| id | doaj.art-259599789915456f9181b94a5ca00b38 |
| institution | Directory Open Access Journal |
| issn | 2081-6936 |
| language | English |
| last_indexed | 2024-04-10T21:30:18Z |
| publishDate | 2022-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Translational Neuroscience |
| spelling | doaj.art-259599789915456f9181b94a5ca00b382023-01-19T13:47:24ZengDe GruyterTranslational Neuroscience2081-69362022-12-0113147047510.1515/tnsci-2022-0263A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case reportZhu Siyao0Zou Yuting1Wang Ya2Xie Gongxun3Xiao Shengying4Zeng Furen5Lu Yichen6Department of Oncology, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), 89 Guhan Road, Furong, Changsha 410002, PR ChinaDepartment of Oncology, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), 89 Guhan Road, Furong, Changsha 410002, PR ChinaDepartment of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, PR ChinaDepartment of Pathology, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410002, PR ChinaDepartment of Oncology, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), 89 Guhan Road, Furong, Changsha 410002, PR ChinaDepartment of Oncology, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), 89 Guhan Road, Furong, Changsha 410002, PR ChinaDepartment of Oncology, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), 89 Guhan Road, Furong, Changsha 410002, PR ChinaLymphoplasmacyte-rich meningioma (LPRM) is a rare subtype of meningioma, the specific pathogenesis of which remains unclear. Herein, we report the case of a 48-year-old Asian man who experienced progressive deafness and limb weakness. Magnetic resonance imaging revealed extramedullary masses diffusely growing, wrapping, and compressing the cervical spinal cord. The dural lesion was partially excised by surgery, and postoperative pathological examination confirmed the diagnosis of LPRM. Diffuse LPRM is extremely rare, and its treatment is challenging owing to difficulties associated with surgery and the uncertain efficacy of traditional therapies. Therefore, further clinical practice and basic research are needed to improve the prognosis of diffuse LPRM.https://doi.org/10.1515/tnsci-2022-0263lymphoplasmacyte-rich meningiomadiffuse growthmagnetic resonance imagingdifferential diagnosistreatment |
| spellingShingle | Zhu Siyao Zou Yuting Wang Ya Xie Gongxun Xiao Shengying Zeng Furen Lu Yichen A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case report Translational Neuroscience lymphoplasmacyte-rich meningioma diffuse growth magnetic resonance imaging differential diagnosis treatment |
| title | A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case report |
| title_full | A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case report |
| title_fullStr | A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case report |
| title_full_unstemmed | A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case report |
| title_short | A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case report |
| title_sort | rare lymphoplasmacyte rich meningioma involving the dura of the skull base and cervical spinal cord a case report |
| topic | lymphoplasmacyte-rich meningioma diffuse growth magnetic resonance imaging differential diagnosis treatment |
| url | https://doi.org/10.1515/tnsci-2022-0263 |
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