The Critical Biomarkers Identification of Insulin Signaling Involved in Initiating cAMP Signaling Mediated Salivary Secretion in Sjogren Syndrome: Transcriptome Sequencing in NOD Mice Model

The Critical Biomarkers Identification of Insulin Signaling Involved in Initiating cAMP Signaling Mediated Salivary Secretion in Sjogren Syndrome: Transcriptome Sequencing in NOD Mice Model

Abstract Background Sjogren’s syndrome (SS) is an autoimmune disorder characterized by the destruction of exocrine glands, resulting in dry mouth and eyes. Currently, there is no effective treatment for SS, and the mechanisms associated with inadequate salivary secretion are poorly understood. Metho...

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Bibliographic Details
Main Authors: Bo Chen, Jiannan Zhou, Tianjiao Mao, Tingting Cao, Shilin Hu, Wenqi Zhang, Xueyang Li, Xiuni Qin, Xintong Liu, Nobumoto Watanabe, Jiang Li
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Biological Procedures Online
Subjects:
Sjogren syndrome (SS)
Insulin signaling
cAMP signaling
Salivary secretion
Biomarkers
NOD mice model
Online Access:https://doi.org/10.1186/s12575-022-00189-5

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