Conjugation of Synthetic Trisaccharide of Staphylococcus aureus Type 8 Capsular Polysaccharide Elicits Antibodies Recognizing Intact Bacterium

Conjugation of Synthetic Trisaccharide of Staphylococcus aureus Type 8 Capsular Polysaccharide Elicits Antibodies Recognizing Intact Bacterium

Staphylococcus aureus causes a wide range of life-threatening diseases. One of the powerful approaches for prevention and treatment is to develop an efficient vaccine as antibiotic resistance greatly increases. S. aureus type 8 capsular polysaccharide (CP8) has shown great potential in vaccine devel...

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Bibliographic Details
Main Authors: Ming Zhao, Chunjun Qin, Lingxin Li, Haotian Xie, Beining Ma, Ziru Zhou, Jian Yin, Jing Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Chemistry
Subjects:
Staphylococcus aureus
capsular polysaccharide
synthetic oligosaccharide
immunogenicity
immunoglobulin G (IgG)
monoclonal antibody
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00258/full

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