The COVID-19 Driving Force: How It Shaped the Evidence of Non-Invasive Respiratory Support

During the COVID-19 pandemic, the use of non-invasive respiratory support (NIRS) became crucial in treating patients with acute hypoxemic respiratory failure. Despite the fear of viral aerosolization, non-invasive respiratory support has gained attention as a way to alleviate ICU overcrowding and re...

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Main Authors: Yorschua Jalil, Martina Ferioli, Martin Dres
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/10/3486
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author Yorschua Jalil
Martina Ferioli
Martin Dres
author_facet Yorschua Jalil
Martina Ferioli
Martin Dres
author_sort Yorschua Jalil
collection DOAJ
description During the COVID-19 pandemic, the use of non-invasive respiratory support (NIRS) became crucial in treating patients with acute hypoxemic respiratory failure. Despite the fear of viral aerosolization, non-invasive respiratory support has gained attention as a way to alleviate ICU overcrowding and reduce the risks associated with intubation. The COVID-19 pandemic has led to an unprecedented increased demand for research, resulting in numerous publications on observational studies, clinical trials, reviews, and meta-analyses in the past three years. This comprehensive narrative overview describes the physiological rationale, pre-COVID-19 evidence, and results of observational studies and randomized control trials regarding the use of high-flow nasal oxygen, non-invasive mechanical ventilation, and continuous positive airway pressure in adult patients with COVID-19 and associated acute hypoxemic respiratory failure. The review also highlights the significance of guidelines and recommendations provided by international societies and the need for further well-designed research to determine the optimal use of NIRS in treating this population.
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spelling doaj.art-2596bc8b761a475f8efc1eb9de3f26db2023-11-18T01:53:50ZengMDPI AGJournal of Clinical Medicine2077-03832023-05-011210348610.3390/jcm12103486The COVID-19 Driving Force: How It Shaped the Evidence of Non-Invasive Respiratory SupportYorschua Jalil0Martina Ferioli1Martin Dres2INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Sorbonne Université, 75006 Paris, FranceINSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Sorbonne Université, 75006 Paris, FranceINSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Sorbonne Université, 75006 Paris, FranceDuring the COVID-19 pandemic, the use of non-invasive respiratory support (NIRS) became crucial in treating patients with acute hypoxemic respiratory failure. Despite the fear of viral aerosolization, non-invasive respiratory support has gained attention as a way to alleviate ICU overcrowding and reduce the risks associated with intubation. The COVID-19 pandemic has led to an unprecedented increased demand for research, resulting in numerous publications on observational studies, clinical trials, reviews, and meta-analyses in the past three years. This comprehensive narrative overview describes the physiological rationale, pre-COVID-19 evidence, and results of observational studies and randomized control trials regarding the use of high-flow nasal oxygen, non-invasive mechanical ventilation, and continuous positive airway pressure in adult patients with COVID-19 and associated acute hypoxemic respiratory failure. The review also highlights the significance of guidelines and recommendations provided by international societies and the need for further well-designed research to determine the optimal use of NIRS in treating this population.https://www.mdpi.com/2077-0383/12/10/3486COVID-19coronaviruscritical carenon-invasive ventilationCPAPhigh-flow nasal cannula
spellingShingle Yorschua Jalil
Martina Ferioli
Martin Dres
The COVID-19 Driving Force: How It Shaped the Evidence of Non-Invasive Respiratory Support
Journal of Clinical Medicine
COVID-19
coronavirus
critical care
non-invasive ventilation
CPAP
high-flow nasal cannula
title The COVID-19 Driving Force: How It Shaped the Evidence of Non-Invasive Respiratory Support
title_full The COVID-19 Driving Force: How It Shaped the Evidence of Non-Invasive Respiratory Support
title_fullStr The COVID-19 Driving Force: How It Shaped the Evidence of Non-Invasive Respiratory Support
title_full_unstemmed The COVID-19 Driving Force: How It Shaped the Evidence of Non-Invasive Respiratory Support
title_short The COVID-19 Driving Force: How It Shaped the Evidence of Non-Invasive Respiratory Support
title_sort covid 19 driving force how it shaped the evidence of non invasive respiratory support
topic COVID-19
coronavirus
critical care
non-invasive ventilation
CPAP
high-flow nasal cannula
url https://www.mdpi.com/2077-0383/12/10/3486
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