The Effect of Patient-Related Factors on the Primary Fixation of PEEK and Titanium Tibial Components: A Population-Based FE Study

Polyetheretherketone (PEEK) is of interest as implant material for cementless tibial total knee arthroplasty (TKA) components due to its potential advantages. One main advantage is that the stiffness of PEEK closely resembles the stiffness of bone, potentially avoiding peri-prosthetic stress-shieldi...

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Main Authors: Corine E. Post, Thom Bitter, Adam Briscoe, Inger van Langen, René Fluit, Nico Verdonschot, Dennis Janssen
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/11/2/116
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author Corine E. Post
Thom Bitter
Adam Briscoe
Inger van Langen
René Fluit
Nico Verdonschot
Dennis Janssen
author_facet Corine E. Post
Thom Bitter
Adam Briscoe
Inger van Langen
René Fluit
Nico Verdonschot
Dennis Janssen
author_sort Corine E. Post
collection DOAJ
description Polyetheretherketone (PEEK) is of interest as implant material for cementless tibial total knee arthroplasty (TKA) components due to its potential advantages. One main advantage is that the stiffness of PEEK closely resembles the stiffness of bone, potentially avoiding peri-prosthetic stress-shielding. When introducing a new implant material for cementless TKA designs, it is essential to study its effect on the primary fixation. The primary fixation may be influenced by patient factors such as age, gender, and body mass index (BMI). Therefore, the research objectives of this finite element (FE) study were to investigate the effect of material (PEEK vs. titanium) and patient characteristics on the primary fixation (i.e., micromotions) of a cementless tibial tray component. A total of 296 FE models of 74 tibiae were created with either PEEK or titanium material properties, under gait and squat loading conditions. Overall, the PEEK models generated larger peak micromotions than the titanium models. Differences were seen in the micromotion distributions between the PEEK and titanium models for both the gait and squat models. The micromotions of all tibial models significantly increased with BMI, while gender and age did not influence micromotions.
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spelling doaj.art-2598635fc3d743b4a8fede959ea2cfbf2024-02-23T15:07:51ZengMDPI AGBioengineering2306-53542024-01-0111211610.3390/bioengineering11020116The Effect of Patient-Related Factors on the Primary Fixation of PEEK and Titanium Tibial Components: A Population-Based FE StudyCorine E. Post0Thom Bitter1Adam Briscoe2Inger van Langen3René Fluit4Nico Verdonschot5Dennis Janssen6Orthopaedic Research Laboratory, Radboud University Medical Center, 6525 GA Nijmegen, The NetherlandsOrthopaedic Research Laboratory, Radboud University Medical Center, 6525 GA Nijmegen, The NetherlandsInvibio Ltd., Thornton Cleveleys FY5 4QD, Lancashire, UKOrthopaedic Research Laboratory, Radboud University Medical Center, 6525 GA Nijmegen, The NetherlandsOrthopaedic Research Laboratory, Radboud University Medical Center, 6525 GA Nijmegen, The NetherlandsOrthopaedic Research Laboratory, Radboud University Medical Center, 6525 GA Nijmegen, The NetherlandsOrthopaedic Research Laboratory, Radboud University Medical Center, 6525 GA Nijmegen, The NetherlandsPolyetheretherketone (PEEK) is of interest as implant material for cementless tibial total knee arthroplasty (TKA) components due to its potential advantages. One main advantage is that the stiffness of PEEK closely resembles the stiffness of bone, potentially avoiding peri-prosthetic stress-shielding. When introducing a new implant material for cementless TKA designs, it is essential to study its effect on the primary fixation. The primary fixation may be influenced by patient factors such as age, gender, and body mass index (BMI). Therefore, the research objectives of this finite element (FE) study were to investigate the effect of material (PEEK vs. titanium) and patient characteristics on the primary fixation (i.e., micromotions) of a cementless tibial tray component. A total of 296 FE models of 74 tibiae were created with either PEEK or titanium material properties, under gait and squat loading conditions. Overall, the PEEK models generated larger peak micromotions than the titanium models. Differences were seen in the micromotion distributions between the PEEK and titanium models for both the gait and squat models. The micromotions of all tibial models significantly increased with BMI, while gender and age did not influence micromotions.https://www.mdpi.com/2306-5354/11/2/116total knee arthroplastypolyetheretherketonecementless tibial knee componentfinite element simulationmicromotionpopulation study
spellingShingle Corine E. Post
Thom Bitter
Adam Briscoe
Inger van Langen
René Fluit
Nico Verdonschot
Dennis Janssen
The Effect of Patient-Related Factors on the Primary Fixation of PEEK and Titanium Tibial Components: A Population-Based FE Study
Bioengineering
total knee arthroplasty
polyetheretherketone
cementless tibial knee component
finite element simulation
micromotion
population study
title The Effect of Patient-Related Factors on the Primary Fixation of PEEK and Titanium Tibial Components: A Population-Based FE Study
title_full The Effect of Patient-Related Factors on the Primary Fixation of PEEK and Titanium Tibial Components: A Population-Based FE Study
title_fullStr The Effect of Patient-Related Factors on the Primary Fixation of PEEK and Titanium Tibial Components: A Population-Based FE Study
title_full_unstemmed The Effect of Patient-Related Factors on the Primary Fixation of PEEK and Titanium Tibial Components: A Population-Based FE Study
title_short The Effect of Patient-Related Factors on the Primary Fixation of PEEK and Titanium Tibial Components: A Population-Based FE Study
title_sort effect of patient related factors on the primary fixation of peek and titanium tibial components a population based fe study
topic total knee arthroplasty
polyetheretherketone
cementless tibial knee component
finite element simulation
micromotion
population study
url https://www.mdpi.com/2306-5354/11/2/116
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