A scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in WHO Southeast Asia region
Antibiotic use (ABU) plays an important role in the proliferation of antimicrobial resistance (AMR). Global antimicrobial consumption in food production is projected to rise by 67% from 2010 to 2030, but available estimates are limited by the scarcity of ABU data and absence of global surveillance s...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | One Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352771422000441 |
| _version_ | 1811178558252384256 |
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| author | Greco Mark Malijan Nopporn Howteerakul Natasha Ali Sukhontha Siri Mondha Kengganpanich Roger Nascimento Ross D. Booton Katherine M.E. Turner Ben S. Cooper Aronrag Meeyai |
| author_facet | Greco Mark Malijan Nopporn Howteerakul Natasha Ali Sukhontha Siri Mondha Kengganpanich Roger Nascimento Ross D. Booton Katherine M.E. Turner Ben S. Cooper Aronrag Meeyai |
| author_sort | Greco Mark Malijan |
| collection | DOAJ |
| description | Antibiotic use (ABU) plays an important role in the proliferation of antimicrobial resistance (AMR). Global antimicrobial consumption in food production is projected to rise by 67% from 2010 to 2030, but available estimates are limited by the scarcity of ABU data and absence of global surveillance systems. The WHO South-East Asia (WHO SEA) region is at high risk of emergence of AMR, likely driven by intensifying farm operations and worsening ABU hotspots. However, little is known about farm-level ABU practices in the region. To summarize emerging evidence and research gaps, we conducted a scoping review of ABU practices following the Arksey and O'Malley methodological framework. We included studies published between 2010 and 2021 on farm-level ABU/AMR in the 11 WHO SEA member states, and databases were last searched on 31 October 2021. Our search strategy identified 184 unique articles, and 25 publications underwent full-text eligibility assessment. Seventeen studies, reported in 18 publications, were included in the scoping review. We found heterogeneity in the categorizations, definitions, and ABU characterization methods used across studies and farm types. Most studies involved poultry, pig, and cattle farms, and only one study examined aquaculture. Most studies evaluated ABU prevalence by asking respondents about the presence or absence of ABU in the farm. Only two studies quantified antibiotic consumption, and sampling bias and lack of standardized data collection methods were identified as key limitations. Emerging evidence that farm workers had difficulty differentiating antibiotics from other substances contributed to the uncertainty about the reliability of self-reported data without other validation techniques. ABU for growth promotion and treatment were prevalent. We found a large overlap in the critically important antibiotics used in farm animals and humans. The ease of access to antibiotics compounded by the difficulties in accessing quality veterinary care and preventive services likely drive inappropriate ABU in complex ways. |
| first_indexed | 2024-04-11T06:20:22Z |
| format | Article |
| id | doaj.art-25986c075beb4baf8e2c2fe0be8a76b8 |
| institution | Directory Open Access Journal |
| issn | 2352-7714 |
| language | English |
| last_indexed | 2024-04-11T06:20:22Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | One Health |
| spelling | doaj.art-25986c075beb4baf8e2c2fe0be8a76b82022-12-22T04:40:36ZengElsevierOne Health2352-77142022-12-0115100412A scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in WHO Southeast Asia regionGreco Mark Malijan0Nopporn Howteerakul1Natasha Ali2Sukhontha Siri3Mondha Kengganpanich4Roger Nascimento5Ross D. Booton6Katherine M.E. Turner7Ben S. Cooper8Aronrag Meeyai9Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX1 3SY, United KingdomDepartment of Epidemiology, Faculty of Public Health, Mahidol University, 420/1 Ratchawithi Rd., Ratchathewi District, Bangkok 10400, ThailandCentre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX1 3SY, United KingdomDepartment of Epidemiology, Faculty of Public Health, Mahidol University, 420/1 Ratchawithi Rd., Ratchathewi District, Bangkok 10400, ThailandDepartment of Health Education and Behavioral Sciences, Faculty of Public Health, Mahidol University, 420/1 Ratchawithi Rd., Ratchathewi District, Bangkok 10400, ThailandCentre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX1 3SY, United KingdomUK Health Security Agency, 133-155 Waterloo Road, London, SE1 8UG, United KingdomUniversity of Bristol, Dolberry, Bristol BS40 5DU, United KingdomCentre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX1 3SY, United Kingdom; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, ThailandCentre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX1 3SY, United Kingdom; Department of Epidemiology, Faculty of Public Health, Mahidol University, 420/1 Ratchawithi Rd., Ratchathewi District, Bangkok 10400, Thailand; Corresponding author at: Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX1 3SY, United Kingdom.Antibiotic use (ABU) plays an important role in the proliferation of antimicrobial resistance (AMR). Global antimicrobial consumption in food production is projected to rise by 67% from 2010 to 2030, but available estimates are limited by the scarcity of ABU data and absence of global surveillance systems. The WHO South-East Asia (WHO SEA) region is at high risk of emergence of AMR, likely driven by intensifying farm operations and worsening ABU hotspots. However, little is known about farm-level ABU practices in the region. To summarize emerging evidence and research gaps, we conducted a scoping review of ABU practices following the Arksey and O'Malley methodological framework. We included studies published between 2010 and 2021 on farm-level ABU/AMR in the 11 WHO SEA member states, and databases were last searched on 31 October 2021. Our search strategy identified 184 unique articles, and 25 publications underwent full-text eligibility assessment. Seventeen studies, reported in 18 publications, were included in the scoping review. We found heterogeneity in the categorizations, definitions, and ABU characterization methods used across studies and farm types. Most studies involved poultry, pig, and cattle farms, and only one study examined aquaculture. Most studies evaluated ABU prevalence by asking respondents about the presence or absence of ABU in the farm. Only two studies quantified antibiotic consumption, and sampling bias and lack of standardized data collection methods were identified as key limitations. Emerging evidence that farm workers had difficulty differentiating antibiotics from other substances contributed to the uncertainty about the reliability of self-reported data without other validation techniques. ABU for growth promotion and treatment were prevalent. We found a large overlap in the critically important antibiotics used in farm animals and humans. The ease of access to antibiotics compounded by the difficulties in accessing quality veterinary care and preventive services likely drive inappropriate ABU in complex ways.http://www.sciencedirect.com/science/article/pii/S2352771422000441Antibiotic useAntimicrobial resistanceAnimal farmsSoutheast AsiaOne healthFarming practices |
| spellingShingle | Greco Mark Malijan Nopporn Howteerakul Natasha Ali Sukhontha Siri Mondha Kengganpanich Roger Nascimento Ross D. Booton Katherine M.E. Turner Ben S. Cooper Aronrag Meeyai A scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in WHO Southeast Asia region One Health Antibiotic use Antimicrobial resistance Animal farms Southeast Asia One health Farming practices |
| title | A scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in WHO Southeast Asia region |
| title_full | A scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in WHO Southeast Asia region |
| title_fullStr | A scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in WHO Southeast Asia region |
| title_full_unstemmed | A scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in WHO Southeast Asia region |
| title_short | A scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in WHO Southeast Asia region |
| title_sort | scoping review of antibiotic use practices and drivers of inappropriate antibiotic use in animal farms in who southeast asia region |
| topic | Antibiotic use Antimicrobial resistance Animal farms Southeast Asia One health Farming practices |
| url | http://www.sciencedirect.com/science/article/pii/S2352771422000441 |
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