The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice

The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice

Abstract Backgrounds The aberrant activation of complement system is critically involved in lupus nephropathy. Recent study showed complement C3 inhibitor was effective in the treatment of lupus nephropathy. In this study, we investigate the effect of a novel complement C3 inhibitor, CRIg/FH, in the...

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Bibliographic Details
Main Authors: Yu Shi, Wen Yao, Li Sun, Guomin Li, Haimei Liu, Peipei Ding, Weiguo Hu, Hong Xu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Nephrology
Subjects:
MRL/lpr
Complement C3 inhibitor
Lupus nephropathy
Online Access:http://link.springer.com/article/10.1186/s12882-019-1599-0

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