Quality of life after Nissen fundoplication in patients with gastroesophageal reflux disease: Comparison between long- and short-term follow-up
Introduction: Nissen fundoplication is the golden standard for surgical treatment of gastroesophageal reflux disease (GERD). Numerous studies report excellent short-term results. However, data regarding long-term quality of life are lacking. The aim of this study is to investigate the long-term qua...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Journal of Minimal Access Surgery |
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| Online Access: | http://www.journalofmas.com/article.asp?issn=0972-9941;year=2018;volume=14;issue=3;spage=213;epage=220;aulast=Castelijns |
| _version_ | 1818535243353686016 |
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| author | P S. S Castelijns J E. H Ponten M C. G vd Poll N D Bouvy J F Smulders |
| author_facet | P S. S Castelijns J E. H Ponten M C. G vd Poll N D Bouvy J F Smulders |
| author_sort | P S. S Castelijns |
| collection | DOAJ |
| description | Introduction: Nissen fundoplication is the golden standard for surgical treatment of gastroesophageal reflux disease (GERD). Numerous studies report excellent short-term results. However, data regarding long-term quality of life are lacking. The aim of this study is to investigate the long-term quality of life after Nissen fundoplication in patients with GERD and to compare this with the short-term results.
Patients and Methods: We retrospectively analysed all patients who underwent laparoscopic Nissen fundoplication for GERD between January 2004 and January 2016. All patients received a validated GERD-Health-Related Quality of Life questionnaire by mail to assess post-operative quality of life. Maximum quality of life is represented by a score of 75. Secondary outcome measures were complications and recurrence rate.
Results: One hundred and seventy-five (77.1%) of the 227 operated patients returned the questionnaire. The median follow-up was 3.7 (0.1–10.3) years. Mean age was 51.6 (range 15–85) and 72 patients were male. We report an excellent quality of life with a median total score of 70 (range 2–75). Re-operation rate was 13.6% (23/169); the re-operation was due to recurrent reflux in 12 patients and due to persistent dysphagia in 11 patients. 91.3% of the re-operations were performed within the first 5 years after surgery. Mortality rate was zero.
Conclusion: We report a large series of single-centre, single-surgeon laparoscopic Nissen fundoplication. Despite the re-operation rate of 13.6%, we found excellent long-term symptomatic outcome. There was no difference between short- and long-term results. |
| first_indexed | 2024-12-11T18:22:14Z |
| format | Article |
| id | doaj.art-259ecb5777334fefb6078774dd24d9ae |
| institution | Directory Open Access Journal |
| issn | 0972-9941 1998-3921 |
| language | English |
| last_indexed | 2024-12-11T18:22:14Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Minimal Access Surgery |
| spelling | doaj.art-259ecb5777334fefb6078774dd24d9ae2022-12-22T00:55:13ZengWolters Kluwer Medknow PublicationsJournal of Minimal Access Surgery0972-99411998-39212018-01-0114321322010.4103/jmas.JMAS_75_17Quality of life after Nissen fundoplication in patients with gastroesophageal reflux disease: Comparison between long- and short-term follow-upP S. S CastelijnsJ E. H PontenM C. G vd PollN D BouvyJ F SmuldersIntroduction: Nissen fundoplication is the golden standard for surgical treatment of gastroesophageal reflux disease (GERD). Numerous studies report excellent short-term results. However, data regarding long-term quality of life are lacking. The aim of this study is to investigate the long-term quality of life after Nissen fundoplication in patients with GERD and to compare this with the short-term results. Patients and Methods: We retrospectively analysed all patients who underwent laparoscopic Nissen fundoplication for GERD between January 2004 and January 2016. All patients received a validated GERD-Health-Related Quality of Life questionnaire by mail to assess post-operative quality of life. Maximum quality of life is represented by a score of 75. Secondary outcome measures were complications and recurrence rate. Results: One hundred and seventy-five (77.1%) of the 227 operated patients returned the questionnaire. The median follow-up was 3.7 (0.1–10.3) years. Mean age was 51.6 (range 15–85) and 72 patients were male. We report an excellent quality of life with a median total score of 70 (range 2–75). Re-operation rate was 13.6% (23/169); the re-operation was due to recurrent reflux in 12 patients and due to persistent dysphagia in 11 patients. 91.3% of the re-operations were performed within the first 5 years after surgery. Mortality rate was zero. Conclusion: We report a large series of single-centre, single-surgeon laparoscopic Nissen fundoplication. Despite the re-operation rate of 13.6%, we found excellent long-term symptomatic outcome. There was no difference between short- and long-term results.http://www.journalofmas.com/article.asp?issn=0972-9941;year=2018;volume=14;issue=3;spage=213;epage=220;aulast=CastelijnsGastroesophageal reflux diseaselaparoscopiclong-term follow-upNissenquality of life |
| spellingShingle | P S. S Castelijns J E. H Ponten M C. G vd Poll N D Bouvy J F Smulders Quality of life after Nissen fundoplication in patients with gastroesophageal reflux disease: Comparison between long- and short-term follow-up Journal of Minimal Access Surgery Gastroesophageal reflux disease laparoscopic long-term follow-up Nissen quality of life |
| title | Quality of life after Nissen fundoplication in patients with gastroesophageal reflux disease: Comparison between long- and short-term follow-up |
| title_full | Quality of life after Nissen fundoplication in patients with gastroesophageal reflux disease: Comparison between long- and short-term follow-up |
| title_fullStr | Quality of life after Nissen fundoplication in patients with gastroesophageal reflux disease: Comparison between long- and short-term follow-up |
| title_full_unstemmed | Quality of life after Nissen fundoplication in patients with gastroesophageal reflux disease: Comparison between long- and short-term follow-up |
| title_short | Quality of life after Nissen fundoplication in patients with gastroesophageal reflux disease: Comparison between long- and short-term follow-up |
| title_sort | quality of life after nissen fundoplication in patients with gastroesophageal reflux disease comparison between long and short term follow up |
| topic | Gastroesophageal reflux disease laparoscopic long-term follow-up Nissen quality of life |
| url | http://www.journalofmas.com/article.asp?issn=0972-9941;year=2018;volume=14;issue=3;spage=213;epage=220;aulast=Castelijns |
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