An upstream YY1 binding site on the HIV-1 LTR contributes to latent infection.

An upstream YY1 binding site on the HIV-1 LTR contributes to latent infection.

During HIV-1 infection a population of latently infected cells is established. This population is the major obstacle preventing total eradication of the virus from AIDS patients. HIV-1 latency is thought to arise by various mechanisms including repressive chromatin modifications. Transcription facto...

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Bibliographic Details
Main Authors: Wendy Bernhard, Kris Barreto, Sheetal Raithatha, Ivan Sadowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792934?pdf=render

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