EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZIN
Aim. Study the effect of laser emission in the red spectrum on growth of methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus, as well as photodynamic effect of photosensitizer photoditazin. Materials and methods. Effect of light of semiconductor red laser (X 660 nm, 100...
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| Format: | Article |
| Language: | Russian |
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Central Research Institute for Epidemiology
2017-04-01
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| Series: | Журнал микробиологии, эпидемиологии и иммунобиологии |
| Subjects: | |
| Online Access: | https://microbiol.elpub.ru/jour/article/view/139 |
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| author | G. E. Bril A. V. Egorova I. O. Bugaeva G. V. Ponomarev |
| author_facet | G. E. Bril A. V. Egorova I. O. Bugaeva G. V. Ponomarev |
| author_sort | G. E. Bril |
| collection | DOAJ |
| description | Aim. Study the effect of laser emission in the red spectrum on growth of methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus, as well as photodynamic effect of photosensitizer photoditazin. Materials and methods. Effect of light of semiconductor red laser (X 660 nm, 100 mW/cm2) at 30, 60, 90 and 180 J/cm2 on growth of S. aureus colonies was determined. Time of exposure - 5, 10, 15 and 30 minutes. In certain series of experiments bacterial cells were sensitized in advance by a water solution of photoditazin at a concentration of 5x 1 O'6 M. Results. Red laser emission was established to cause a pronouncec suppression of bacterial growth. This effect on standard S. aureus strain only took place during use of relatively high exposure doses (180 J/cm2). Photosensitivity of methicillin-resistan: strain turned out to be significantly higher: bacteriostatic effect of red light was noted alreadx at the dose of 60 J/cm2. Treatment of bacterial cells with photoditazin in advance significantly enhanced growth-inhibiting effect of laser light. |
| first_indexed | 2024-04-13T02:33:43Z |
| format | Article |
| id | doaj.art-25a66dc2390b415baf73276f6a63695f |
| institution | Directory Open Access Journal |
| issn | 0372-9311 2686-7613 |
| language | Russian |
| last_indexed | 2024-04-13T02:33:43Z |
| publishDate | 2017-04-01 |
| publisher | Central Research Institute for Epidemiology |
| record_format | Article |
| series | Журнал микробиологии, эпидемиологии и иммунобиологии |
| spelling | doaj.art-25a66dc2390b415baf73276f6a63695f2022-12-22T03:06:27ZrusCentral Research Institute for EpidemiologyЖурнал микробиологии, эпидемиологии и иммунобиологии0372-93112686-76132017-04-0102343710.36233/0372-9311-2017-2-34-37139EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZING. E. Bril0A. V. Egorova1I. O. Bugaeva2G. V. Ponomarev3Razumovsky Saratov State Medical UniversityRazumovsky Saratov State Medical UniversityRazumovsky Saratov State Medical UniversityOrekhovich Institute of Biomedical ChemistryAim. Study the effect of laser emission in the red spectrum on growth of methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus, as well as photodynamic effect of photosensitizer photoditazin. Materials and methods. Effect of light of semiconductor red laser (X 660 nm, 100 mW/cm2) at 30, 60, 90 and 180 J/cm2 on growth of S. aureus colonies was determined. Time of exposure - 5, 10, 15 and 30 minutes. In certain series of experiments bacterial cells were sensitized in advance by a water solution of photoditazin at a concentration of 5x 1 O'6 M. Results. Red laser emission was established to cause a pronouncec suppression of bacterial growth. This effect on standard S. aureus strain only took place during use of relatively high exposure doses (180 J/cm2). Photosensitivity of methicillin-resistan: strain turned out to be significantly higher: bacteriostatic effect of red light was noted alreadx at the dose of 60 J/cm2. Treatment of bacterial cells with photoditazin in advance significantly enhanced growth-inhibiting effect of laser light.https://microbiol.elpub.ru/jour/article/view/139staphylococcus aureusstaphylococcus aureuslaser emissionphotoditazin |
| spellingShingle | G. E. Bril A. V. Egorova I. O. Bugaeva G. V. Ponomarev EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZIN Журнал микробиологии, эпидемиологии и иммунобиологии staphylococcus aureus staphylococcus aureus laser emission photoditazin |
| title | EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZIN |
| title_full | EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZIN |
| title_fullStr | EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZIN |
| title_full_unstemmed | EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZIN |
| title_short | EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUS AND SENSITIZING EFFECT OF PHOTODITAZIN |
| title_sort | effect of low intensity red laser on growth of staphylococcus aureus and sensitizing effect of photoditazin |
| topic | staphylococcus aureus staphylococcus aureus laser emission photoditazin |
| url | https://microbiol.elpub.ru/jour/article/view/139 |
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