CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion
Abstract: CHILD syndrome (Congenital Hemidysplasia, Ichthyosiform erythroderma, Limb Defects) is a rare X-linked dominant disease. The authors report a 2-month-old patient presenting with typical features of CHILD syndrome that was treated with a topical solution containing cholesterol and lovastati...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Dermatologia
2019-07-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000300341&tlng=en |
| _version_ | 1798019264152600576 |
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| author | Karina Romero Sandoval Maria Cecília Rivitti Machado Zilda Najjar Prado de Oliveira Marcello Menta Simonsen Nico |
| author_facet | Karina Romero Sandoval Maria Cecília Rivitti Machado Zilda Najjar Prado de Oliveira Marcello Menta Simonsen Nico |
| author_sort | Karina Romero Sandoval |
| collection | DOAJ |
| description | Abstract: CHILD syndrome (Congenital Hemidysplasia, Ichthyosiform erythroderma, Limb Defects) is a rare X-linked dominant disease. The authors report a 2-month-old patient presenting with typical features of CHILD syndrome that was treated with a topical solution containing cholesterol and lovastatin, with complete clearance of her CHILD nevus. The changes in skin lipid metabolism that explain the CHILD ichthyosiform nevus and their correction through topical application of cholesterol and lovastatin are discussed. |
| first_indexed | 2024-04-11T16:37:56Z |
| format | Article |
| id | doaj.art-25a73f8d02b74b1bba521e2b36a90ab9 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-04-11T16:37:56Z |
| publishDate | 2019-07-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-25a73f8d02b74b1bba521e2b36a90ab92022-12-22T04:13:45ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962019-07-0194334134310.1590/abd1806-4841.20198789CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotionKarina Romero Sandovalhttps://orcid.org/0000-0001-7671-5019Maria Cecília Rivitti Machadohttps://orcid.org/0000-0003-2910-7330Zilda Najjar Prado de Oliveirahttps://orcid.org/0000-0002-8596-1999Marcello Menta Simonsen Nicohttps://orcid.org/0000-0001-7968-0624Abstract: CHILD syndrome (Congenital Hemidysplasia, Ichthyosiform erythroderma, Limb Defects) is a rare X-linked dominant disease. The authors report a 2-month-old patient presenting with typical features of CHILD syndrome that was treated with a topical solution containing cholesterol and lovastatin, with complete clearance of her CHILD nevus. The changes in skin lipid metabolism that explain the CHILD ichthyosiform nevus and their correction through topical application of cholesterol and lovastatin are discussed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000300341&tlng=enCholesterolIchthyosisLovastatin |
| spellingShingle | Karina Romero Sandoval Maria Cecília Rivitti Machado Zilda Najjar Prado de Oliveira Marcello Menta Simonsen Nico CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion Anais Brasileiros de Dermatologia Cholesterol Ichthyosis Lovastatin |
| title | CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion |
| title_full | CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion |
| title_fullStr | CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion |
| title_full_unstemmed | CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion |
| title_short | CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion |
| title_sort | child syndrome successful treatment of skin lesions with topical lovastatin and cholesterol lotion |
| topic | Cholesterol Ichthyosis Lovastatin |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000300341&tlng=en |
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