Herp regulates intracellular survival of Mycobacterium tuberculosis H37Ra in macrophages by regulating reactive oxygen species-mediated autophagy

Herp regulates intracellular survival of Mycobacterium tuberculosis H37Ra in macrophages by regulating reactive oxygen species-mediated autophagy

ABSTRACT Novel treatment strategies for tuberculosis (TB), such as host-directed therapeutics, may offer therapeutic options for patients with drug-resistant TB. Endoplasmic reticulum (ER) stress-mediated apoptosis is one of the host defense mechanisms used to remove mycobacteria. It is reported tha...

Полное описание

Библиографические подробности
Главные авторы: Sang-Hun Son, Junghwan Lee, Soo-Na Cho, Ji-Ae Choi, Jaewhan Kim, Tam Doan Nguyen, Seong-Ahn Lee, Doyi Son, Chang-Hwa Song
Формат: Статья
Язык:English
Опубликовано: American Society for Microbiology 2023-10-01
Серии:mBio
Предметы:
ER stress
Mycobacterium tuberculosis
homocysteine-inducible ER protein with ubiquitin-like domain 1
reactive oxygen species
ER-associated degradation
autophagy
Online-ссылка:https://journals.asm.org/doi/10.1128/mbio.01535-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01535-23

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